Abstract
Hyperpigmented macules in children can be the first clinical sign of an underlying condition or syndrome. Café au lait maculae and lentigines are well-known examples. Café au lait maculae may be associated with syndromes such as neurofibromatosis type 1, Legius syndrome and McCune-Albright syndrome. Lentigines are seen in Peutz-Jeghers syndrome and Noonan syndrome with multiple lentigines (LEOPARD syndrome). Early diagnosis is important to agree on appropriate screening and surveillance for these children.
| Translated title of the contribution | Hyperpigmented macules in children as a manifestation of a syndrome: A clinical approach |
|---|---|
| Original language | Dutch |
| Pages (from-to) | 20-23 |
| Number of pages | 4 |
| Journal | Nederlands Tijdschrift voor Dermatologie en Venereologie |
| Volume | 32 |
| Issue number | 4 |
| Publication status | Published - 2022 |
Keywords
- café au lait macules
- genetic syndromes of pigmentation
- hyperpigmentation
- lentigines
- neurofibromatosis