TY - JOUR
T1 - Physical performance tasks were linked to the PROMIS physical function metric in patients undergoing hemodialysis
AU - Liegl, Gregor
AU - Fischer, Felix H
AU - Woodward, Mark
AU - Török, Marietta
AU - Strippoli, Giovanni F M
AU - Hegbrant, Jörgen
AU - Davenport, Andrew
AU - Cromm, Krister
AU - Canaud, Bernard
AU - Bots, Michiel L
AU - Blankestijn, Peter J
AU - Barth, Claudia
AU - Fischer, Kathrin I
AU - Rose, Matthias
N1 - Publisher Copyright:
© 2023 The Authors
PY - 2023/7
Y1 - 2023/7
N2 - OBJECTIVES: To investigate whether a multi-item performance outcome measure, the physical performance test (PPT), can be calibrated to a common scale with patient-reported outcome measures, using the Patient-Reported Outcomes Measurement Information System (PROMIS) physical function (PF) metric.STUDY DESIGN AND SETTING: We analyzed baseline data (N = 1,113) from the CONVINCE study, an international trial in end-stage kidney disease patients comparing high-dose hemodiafiltration with high-flux hemodialysis. Assumptions of item response theory (IRT) modelling were investigated for the combined set of the nine-item PPT and a four-item PROMIS PF short form (PROMIS-PF4a). We applied unidimensional IRT linking for calibrating the PPT to the PROMIS PF metric.RESULTS: Although some evidence for multidimensionality was found, classical test statistics (Cronbach's Alpha = 0.93), Mokken (Loevinger's H = 0.50), and bifactor analysis (explained common variance = 0.65) indicated that PPT and PROMIS-PF4a items can be used to assess a common PF construct. On the group level, the agreement between PROMIS-PF4a and linked PPT scores was stable across several subsamples. On the individual level, scores differed considerably.CONCLUSION: We found preliminary evidence that the PPT can be linked to the PROMIS PF metric in hemodialysis patients, enabling group comparisons across patient-reported outcome and performance outcome measures. Alternative linking methods should be applied in future studies using a more comprehensive PROMIS PF item set.
AB - OBJECTIVES: To investigate whether a multi-item performance outcome measure, the physical performance test (PPT), can be calibrated to a common scale with patient-reported outcome measures, using the Patient-Reported Outcomes Measurement Information System (PROMIS) physical function (PF) metric.STUDY DESIGN AND SETTING: We analyzed baseline data (N = 1,113) from the CONVINCE study, an international trial in end-stage kidney disease patients comparing high-dose hemodiafiltration with high-flux hemodialysis. Assumptions of item response theory (IRT) modelling were investigated for the combined set of the nine-item PPT and a four-item PROMIS PF short form (PROMIS-PF4a). We applied unidimensional IRT linking for calibrating the PPT to the PROMIS PF metric.RESULTS: Although some evidence for multidimensionality was found, classical test statistics (Cronbach's Alpha = 0.93), Mokken (Loevinger's H = 0.50), and bifactor analysis (explained common variance = 0.65) indicated that PPT and PROMIS-PF4a items can be used to assess a common PF construct. On the group level, the agreement between PROMIS-PF4a and linked PPT scores was stable across several subsamples. On the individual level, scores differed considerably.CONCLUSION: We found preliminary evidence that the PPT can be linked to the PROMIS PF metric in hemodialysis patients, enabling group comparisons across patient-reported outcome and performance outcome measures. Alternative linking methods should be applied in future studies using a more comprehensive PROMIS PF item set.
KW - Humans
KW - Outcome Assessment, Health Care
KW - Patient Reported Outcome Measures
KW - Physical Functional Performance
KW - Renal Dialysis
KW - Surveys and Questionnaires
UR - http://www.scopus.com/inward/record.url?scp=85162167612&partnerID=8YFLogxK
U2 - 10.1016/j.jclinepi.2023.04.007
DO - 10.1016/j.jclinepi.2023.04.007
M3 - Article
C2 - 37105321
SN - 0895-4356
VL - 159
SP - 128
EP - 138
JO - Journal of Clinical Epidemiology
JF - Journal of Clinical Epidemiology
ER -