Phase I Pharmacokinetic and Pharmacodynamic Study of the Oral Protein Kinase C ß-Inhibitor Enzastaurin in Combination with Gemcitabine and Cisplatin in Patients with Advanced Cancer

J.M. Rademaker-Lakhai; L.V. Beerepoot; N. Mehra; S.A Radema; R. van Maanen; J.S. Vermaat; E.O. Witteveen; C.M. Visseren-Grul; L. Musib; N. Enas; G. van Hal; J.H. Beijnen; J.H.M. Schellens; E.E. Voest

doi:10.1158/1078-0432.CCR-06-2912

Phase I Pharmacokinetic and Pharmacodynamic Study of the Oral Protein Kinase C ß-Inhibitor Enzastaurin in Combination with Gemcitabine and Cisplatin in Patients with Advanced Cancer

Translated title of the contribution: Phase I Pharmacokinetic and Pharmacodynamic Study of the Oral Protein Kinase C ß-Inhibitor Enzastaurin in Combination with Gemcitabine and Cisplatin in Patients with Advanced Cancer

J.M. Rademaker-Lakhai, L.V. Beerepoot, N. Mehra, S.A Radema, R. van Maanen, J.S. Vermaat, E.O. Witteveen, C.M. Visseren-Grul, L. Musib, N. Enas, G. van Hal, J.H. Beijnen, J.H.M. Schellens, E.E. Voest

Research output: Contribution to journal › Article › Academic › peer-review

Translated title of the contribution	Phase I Pharmacokinetic and Pharmacodynamic Study of the Oral Protein Kinase C ß-Inhibitor Enzastaurin in Combination with Gemcitabine and Cisplatin in Patients with Advanced Cancer
Original language	Undefined/Unknown
Pages (from-to)	4474-4481
Number of pages	8
Journal	Clinical Cancer Research
Volume	13
Issue number	15
DOIs	https://doi.org/10.1158/1078-0432.CCR-06-2912
Publication status	Published - 2007

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10.1158/1078-0432.CCR-06-2912

Cite this

Rademaker-Lakhai, J. M., Beerepoot, L. V., Mehra, N., Radema, S. A., van Maanen, R., Vermaat, J. S., Witteveen, E. O., Visseren-Grul, C. M., Musib, L., Enas, N., van Hal, G., Beijnen, J. H., Schellens, J. H. M., & Voest, E. E. (2007). Phase I Pharmacokinetic and Pharmacodynamic Study of the Oral Protein Kinase C ß-Inhibitor Enzastaurin in Combination with Gemcitabine and Cisplatin in Patients with Advanced Cancer. Clinical Cancer Research, 13(15), 4474-4481. https://doi.org/10.1158/1078-0432.CCR-06-2912

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title = "Phase I Pharmacokinetic and Pharmacodynamic Study of the Oral Protein Kinase C {\ss}-Inhibitor Enzastaurin in Combination with Gemcitabine and Cisplatin in Patients with Advanced Cancer",

author = "J.M. Rademaker-Lakhai and L.V. Beerepoot and N. Mehra and S.A Radema and {van Maanen}, R. and J.S. Vermaat and E.O. Witteveen and C.M. Visseren-Grul and L. Musib and N. Enas and {van Hal}, G. and J.H. Beijnen and J.H.M. Schellens and E.E. Voest",

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language = "Undefined/Unknown",

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Rademaker-Lakhai, JM, Beerepoot, LV, Mehra, N, Radema, SA, van Maanen, R, Vermaat, JS, Witteveen, EO, Visseren-Grul, CM, Musib, L, Enas, N, van Hal, G, Beijnen, JH, Schellens, JHM & Voest, EE 2007, 'Phase I Pharmacokinetic and Pharmacodynamic Study of the Oral Protein Kinase C ß-Inhibitor Enzastaurin in Combination with Gemcitabine and Cisplatin in Patients with Advanced Cancer', Clinical Cancer Research, vol. 13, no. 15, pp. 4474-4481. https://doi.org/10.1158/1078-0432.CCR-06-2912

Phase I Pharmacokinetic and Pharmacodynamic Study of the Oral Protein Kinase C ß-Inhibitor Enzastaurin in Combination with Gemcitabine and Cisplatin in Patients with Advanced Cancer. / Rademaker-Lakhai, J.M.; Beerepoot, L.V.; Mehra, N. et al.
In: Clinical Cancer Research, Vol. 13, No. 15, 2007, p. 4474-4481.

Research output: Contribution to journal › Article › Academic › peer-review

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T1 - Phase I Pharmacokinetic and Pharmacodynamic Study of the Oral Protein Kinase C ß-Inhibitor Enzastaurin in Combination with Gemcitabine and Cisplatin in Patients with Advanced Cancer

AU - Rademaker-Lakhai, J.M.

AU - Beerepoot, L.V.

AU - Mehra, N.

AU - Radema, S.A

AU - van Maanen, R.

AU - Vermaat, J.S.

AU - Witteveen, E.O.

AU - Visseren-Grul, C.M.

AU - Musib, L.

AU - Enas, N.

AU - van Hal, G.

AU - Beijnen, J.H.

AU - Schellens, J.H.M.

AU - Voest, E.E.

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PY - 2007

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U2 - 10.1158/1078-0432.CCR-06-2912

DO - 10.1158/1078-0432.CCR-06-2912

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C2 - 17671132

SN - 1078-0432

VL - 13

SP - 4474

EP - 4481

JO - Clinical Cancer Research

JF - Clinical Cancer Research

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