Petrified heart in a patient with Wolfram Syndrome

Agnese Siani, Mirela Proaspatu, Giuseppe Lanzo, Paolo Irico, Sara Rodolfi, Serena Carriero, Marco Guglielmo*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Myocardial calcification is a rare complication of severe systemic sepsis. The pathophysiological mechanisms underlying calcium accumulation in cardiomyocytes in generalized sepsis are complex and still under investigation. It is a serious and life-threatening condition, usually diagnosed by autopsy, rarely with imaging techniques. We describe the case of a 38-year-old woman with Wolfram Syndrome who developed diffuse myocardial calcification during an episode of generalized sepsis.

Original languageEnglish
JournalJournal of Public Health Research
Volume11
Issue number3
DOIs
Publication statusPublished - Jul 2022
Externally publishedYes

Keywords

  • computed tomography (CT)
  • Myocardial calcification
  • sepsis
  • Wolfram Syndrome

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