Percutaneous closure of a patent foramen ovale: Single-centre experience using different types of devices and mid-term outcome

Martijn C. Post, Kristien Van Deyk, Werner Budts*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

51 Citations (Scopus)

Abstract

Introduction - Patent foramen ovale (PFO) has been identified as a source of paradoxical embolism and cryptogenic stroke. Low recurrence rates of ischaemic stroke after percutaneous closure have been described. We report our single-centre experience using four different types of devices. Methods - All patients, who underwent a percutaneous PFO closure in the University Hospitals Leuven between February 1999 and December 2003, were included. The primary end point was defined as reoccurrence of stroke, transient ischaemic attack (TIA), or a peripheral thrombo-embolic event. The periprocedural and mid-term complications were reported. Results - One-hundred and twelve patients, mean age 52.1 ± 12.5 years (63 men/49 women), were included in the study. Indications for closure were cryptogenic stroke (91.9%), peripheral embolism (4.5%), obligate right-to-left shunt in Ebstein anomaly (1.8%), platypnoea syndrome or brain abscesses (both 0.9%). The Cardioseal/Starflex® was used in 12, the Amplatzer PFO occluder® in 35, the PFO-Star/CardiaStar® in 64, and the Helex® in one patient. The primary end point occurred in 1.8% for stroke and 2.8% for TIA during a median follow-up of 1.9 years, range 4.9 years. Periprocedural complications were dislocation of the device (0.9%), transient arrhythmias (15.5%), aspiration pneumonia (0.9%), inguinal haematoma (3.6%), and an allergic reaction to medication (1.8%). Mid-term complications were perforation of the device (0.9%), persistent transient arrhythmias (6.3%) and thrombus formation on the device (0.9%). No significant differences in outcome or the occurrence of any type of complication could be documented between the different types of devices. Conclusion - Percutaneous PFO closure seems to be a highly efficient and relatively safe procedure, independent of the type of device used for closure.

Original languageEnglish
Pages (from-to)515-519
Number of pages5
JournalActa Cardiologica
Volume60
Issue number5
DOIs
Publication statusPublished - 1 Oct 2005
Externally publishedYes

Keywords

  • Cryptogenic stroke
  • Left-to-right shunt
  • Potent foramen ovale

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