TY - JOUR
T1 - Patterns of obsessive-compulsive symptoms and social functioning in schizophrenia; a replication study
AU - Swets, Marije
AU - van Dijk, Floor A.
AU - Schirmbeck, Frederike
AU - Peen, Jaap
AU - de Haan, Lieuwe
AU - Alizadeh, Behrooz Z.
AU - van Amelsvoort, Therese
AU - Bartels-Velthuis, Agna A.
AU - van Beveren, Nico J.
AU - Bruggeman, Richard
AU - Cahn, Wiepke
AU - Delespaul, Philippe
AU - Luykx, Jurjen J.
AU - Myin-Germeys, Inez
AU - Kahn, Rene S.
AU - Simons, Claudia J.P.
AU - van Haren, Neeltje E.
AU - van Os, Jim
AU - van Winkel, Ruud
N1 - Publisher Copyright:
© 2018
PY - 2019/1/1
Y1 - 2019/1/1
N2 - Research has found that Obsessive Compulsive Symptoms (OCS) in schizophrenia are associated with either more or less negative symptoms and either better or poorer cognitive functioning. In order to explain these contradictory results, (Lysaker et al., 2004), performed a cluster analysis resulting in 2 OCS positive (OCSpos) clusters, one with higher functioning (HF) and one with poorer functioning (PF) compared to 2 OCS negative (OCSneg) clusters. The OCSpos/HF cluster had less negative symptoms compared to all other clusters, while the OCSpos/PF cluster showed poorer executive functioning. We performed a replication study, in an almost 10 times larger, representative sample, using both a longitudinal and cross-sectional design. Similar to Lysaker et al., we found a group with mild OCS and HF (OCSmild/HF) showing less negative symptoms compared to the PF groups. We also found an OCSmild/PF group, which did not significantly differ in executive functioning from the other groups. Moreover, we did not find evidence for a better prognosis in the OCSmild/HF group, and thus found no support for the assumption that for some patients OCS might be an effective coping mechanism.
AB - Research has found that Obsessive Compulsive Symptoms (OCS) in schizophrenia are associated with either more or less negative symptoms and either better or poorer cognitive functioning. In order to explain these contradictory results, (Lysaker et al., 2004), performed a cluster analysis resulting in 2 OCS positive (OCSpos) clusters, one with higher functioning (HF) and one with poorer functioning (PF) compared to 2 OCS negative (OCSneg) clusters. The OCSpos/HF cluster had less negative symptoms compared to all other clusters, while the OCSpos/PF cluster showed poorer executive functioning. We performed a replication study, in an almost 10 times larger, representative sample, using both a longitudinal and cross-sectional design. Similar to Lysaker et al., we found a group with mild OCS and HF (OCSmild/HF) showing less negative symptoms compared to the PF groups. We also found an OCSmild/PF group, which did not significantly differ in executive functioning from the other groups. Moreover, we did not find evidence for a better prognosis in the OCSmild/HF group, and thus found no support for the assumption that for some patients OCS might be an effective coping mechanism.
UR - http://www.scopus.com/inward/record.url?scp=85057713693&partnerID=8YFLogxK
U2 - 10.1016/j.psychres.2018.11.071
DO - 10.1016/j.psychres.2018.11.071
M3 - Article
C2 - 30537664
SN - 0165-1781
VL - 271
SP - 421
EP - 427
JO - Psychiatry Research
JF - Psychiatry Research
ER -