Pathology of intraductal papillary mucinous neoplasms

Naziheh Assarzadegan; Elizabeth Thompson; Kevan Salimian; Matthias M Gaida; Lodewijk A A Brosens; Laura Wood; Syed Z Ali; Ralph H Hruban

doi:10.1007/s00423-021-02201-0

Pathology of intraductal papillary mucinous neoplasms

Naziheh Assarzadegan
, Elizabeth Thompson
, Kevan Salimian
, Matthias M Gaida
, Lodewijk A A Brosens
, Laura Wood
, Syed Z Ali
, Ralph H Hruban

Research output: Contribution to journal › Review article › peer-review

Abstract

BACKGROUND: Intraductal papillary mucinous neoplasms (IPMNs) represent a unique opportunity to treat and prevent a curable neoplasm before it has the chance to progress to incurable cancer. This prospect, however, has to be balanced with the real risk of over treating patients with lesions that would, in fact, never progress during the life of the patient.

PURPOSE: Informed clinical decisions in the treatment of IPMNs are first and foremost based on a deep understanding of the pathology of these lesions.

CONCLUSIONS: Here we review the pathology of IPMNs, with an emphasis on the clinical relevance of the important features that characterize these lesions.

Original language	English
Pages (from-to)	2643-2655
Number of pages	13
Journal	Langenbeck's Archives of Surgery
Volume	406
Issue number	8
Early online date	28 May 2021
DOIs	https://doi.org/10.1007/s00423-021-02201-0
Publication status	Published - Dec 2021

Keywords

Intraductal oncocytic papillary neoplasm
Intraductal papillary mucinous neoplasm
Intraductal tubulopapillary neoplasm
Pancreas cancer
Pancreatic cancer
Pathology

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10.1007/s00423-021-02201-0

Assarzadegan2021_Article_PathologyOfIntraductalPapillarFinal published version, 7.53 MBLicence: Taverne

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title = "Pathology of intraductal papillary mucinous neoplasms",

abstract = "BACKGROUND: Intraductal papillary mucinous neoplasms (IPMNs) represent a unique opportunity to treat and prevent a curable neoplasm before it has the chance to progress to incurable cancer. This prospect, however, has to be balanced with the real risk of over treating patients with lesions that would, in fact, never progress during the life of the patient.PURPOSE: Informed clinical decisions in the treatment of IPMNs are first and foremost based on a deep understanding of the pathology of these lesions.CONCLUSIONS: Here we review the pathology of IPMNs, with an emphasis on the clinical relevance of the important features that characterize these lesions.",

keywords = "Intraductal oncocytic papillary neoplasm, Intraductal papillary mucinous neoplasm, Intraductal tubulopapillary neoplasm, Pancreas cancer, Pancreatic cancer, Pathology",

author = "Naziheh Assarzadegan and Elizabeth Thompson and Kevan Salimian and Gaida, \{Matthias M\} and Brosens, \{Lodewijk A A\} and Laura Wood and Ali, \{Syed Z\} and Hruban, \{Ralph H\}",

note = "Publisher Copyright: {\textcopyright} 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.",

year = "2021",

month = dec,

doi = "10.1007/s00423-021-02201-0",

language = "English",

volume = "406",

pages = "2643--2655",

journal = "Langenbeck's Archives of Surgery",

issn = "1435-2443",

publisher = "Springer Science and Business Media Deutschland GmbH",

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TY - JOUR

T1 - Pathology of intraductal papillary mucinous neoplasms

AU - Assarzadegan, Naziheh

AU - Thompson, Elizabeth

AU - Salimian, Kevan

AU - Gaida, Matthias M

AU - Brosens, Lodewijk A A

AU - Wood, Laura

AU - Ali, Syed Z

AU - Hruban, Ralph H

PY - 2021/12

Y1 - 2021/12

N2 - BACKGROUND: Intraductal papillary mucinous neoplasms (IPMNs) represent a unique opportunity to treat and prevent a curable neoplasm before it has the chance to progress to incurable cancer. This prospect, however, has to be balanced with the real risk of over treating patients with lesions that would, in fact, never progress during the life of the patient.PURPOSE: Informed clinical decisions in the treatment of IPMNs are first and foremost based on a deep understanding of the pathology of these lesions.CONCLUSIONS: Here we review the pathology of IPMNs, with an emphasis on the clinical relevance of the important features that characterize these lesions.

AB - BACKGROUND: Intraductal papillary mucinous neoplasms (IPMNs) represent a unique opportunity to treat and prevent a curable neoplasm before it has the chance to progress to incurable cancer. This prospect, however, has to be balanced with the real risk of over treating patients with lesions that would, in fact, never progress during the life of the patient.PURPOSE: Informed clinical decisions in the treatment of IPMNs are first and foremost based on a deep understanding of the pathology of these lesions.CONCLUSIONS: Here we review the pathology of IPMNs, with an emphasis on the clinical relevance of the important features that characterize these lesions.

KW - Intraductal oncocytic papillary neoplasm

KW - Intraductal papillary mucinous neoplasm

KW - Intraductal tubulopapillary neoplasm

KW - Pancreas cancer

KW - Pancreatic cancer

KW - Pathology

UR - https://www.scopus.com/pages/publications/85106706223

U2 - 10.1007/s00423-021-02201-0

DO - 10.1007/s00423-021-02201-0

M3 - Review article

C2 - 34047827

SN - 1435-2443

VL - 406

SP - 2643

EP - 2655

JO - Langenbeck's Archives of Surgery

JF - Langenbeck's Archives of Surgery

IS - 8

ER -

Pathology of intraductal papillary mucinous neoplasms

Abstract

Keywords

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