Paediatric Onco-Critical CarePOKER (PICU Oncology Kids in Europe Research Group), a Section of ESPNIC

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Abstract

With more than 3.7 million new cases and 1.9 million deaths each year among adults and children, cancer represents the second most important cause of death and morbidity in Europe among all age groups. New treatments—from precision medicine to immunotherapy—have translated into improved survival and cure rates: currently, 5-year all-cancer survival has increased to almost 80% in children. Despite this progress, death rates from cancer remain substantial and challenging due to cancer-related and treatment-related complications. This chapter describes the most important emergencies and complications requiring PICU admissions in paediatric cancer patients.

Original languageEnglish
Title of host publicationESPNIC Children’s Intensive Care Textbook
PublisherSpringer Science+Business Media
Pages723-751
Number of pages29
ISBN (Electronic)9783031647628
ISBN (Print)9783031647611
DOIs
Publication statusPublished - 2 Jul 2025

Keywords

  • Cancer
  • Cytokine release syndrome
  • Haemophagocytic lymphohistiocytosis
  • Hyperleukocytosis
  • Intracranial hypertension
  • Mediastinal tumours
  • Posterior reversible encephalopathy syndrome
  • Sepsis
  • Tumour lysis syndrome

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