Organoid models of childhood kidney tumours

Ariadne H.A.G. Ooms; Camilla Calandrini; Ronald R. de Krijger; Jarno Drost

doi:10.1038/s41585-020-0315-y

Organoid models of childhood kidney tumours

Ariadne H.A.G. Ooms
, Camilla Calandrini
, Ronald R. de Krijger
, Jarno Drost^*

^*Corresponding author for this work

Research output: Contribution to journal › Comment/Letter to the editor › Academic › peer-review

Abstract

Paediatric kidney tumours comprise many different subtypes, each being heterogeneous in their cellular as well as genetic composition. Advances in the past decade in 3D culture models create new opportunities for the generation of preclinical models capturing this phenotypic and genetic heterogeneity, potentially enabling the generation of patient-tailored therapies.

Original language	English
Pages (from-to)	311-313
Number of pages	3
Journal	Nature Reviews Urology
Volume	17
Issue number	6
DOIs	https://doi.org/10.1038/s41585-020-0315-y
Publication status	Published - 1 Jun 2020

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title = "Organoid models of childhood kidney tumours",

abstract = "Paediatric kidney tumours comprise many different subtypes, each being heterogeneous in their cellular as well as genetic composition. Advances in the past decade in 3D culture models create new opportunities for the generation of preclinical models capturing this phenotypic and genetic heterogeneity, potentially enabling the generation of patient-tailored therapies.",

author = "Ooms, \{Ariadne H.A.G.\} and Camilla Calandrini and \{de Krijger\}, \{Ronald R.\} and Jarno Drost",

year = "2020",

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doi = "10.1038/s41585-020-0315-y",

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journal = "Nature Reviews Urology",

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T1 - Organoid models of childhood kidney tumours

AU - Ooms, Ariadne H.A.G.

AU - Calandrini, Camilla

AU - de Krijger, Ronald R.

AU - Drost, Jarno

PY - 2020/6/1

Y1 - 2020/6/1

N2 - Paediatric kidney tumours comprise many different subtypes, each being heterogeneous in their cellular as well as genetic composition. Advances in the past decade in 3D culture models create new opportunities for the generation of preclinical models capturing this phenotypic and genetic heterogeneity, potentially enabling the generation of patient-tailored therapies.

AB - Paediatric kidney tumours comprise many different subtypes, each being heterogeneous in their cellular as well as genetic composition. Advances in the past decade in 3D culture models create new opportunities for the generation of preclinical models capturing this phenotypic and genetic heterogeneity, potentially enabling the generation of patient-tailored therapies.

UR - https://www.scopus.com/pages/publications/85083058696

U2 - 10.1038/s41585-020-0315-y

DO - 10.1038/s41585-020-0315-y

M3 - Comment/Letter to the editor

C2 - 32242130

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SN - 1759-4812

VL - 17

SP - 311

EP - 313

JO - Nature Reviews Urology

JF - Nature Reviews Urology

IS - 6

ER -

Organoid models of childhood kidney tumours

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