Omgaan met kleine relatieve risico's in wetenschap en beleid: De 3e- generatiepil

Translated title of the contribution: Handling small relative risks in science and management: The third- generation pill

J. P. Vandenbroucke*, K. W.M. Bloemenkamp, F. M. Helmerhorst, F. R. Rosendaal

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

4 Citations (Scopus)

Abstract

Small relative risks (a twofold or lesser increase in disease frequency) become scientifically acceptable with (a) repeated consistent findings from studies that (b) address the most important forms of bias and confounding, and (c) when there is a plausible biologic mechanism. The third-generation oral contraceptive controversy is an example of such a relevant but small relative risk and demonstrates the problem of interpretation and implementation into medical practice guidelines.

Translated title of the contributionHandling small relative risks in science and management: The third- generation pill
Original languageDutch
Pages (from-to)254-258
Number of pages5
JournalNederlands Tijdschrift voor Geneeskunde
Volume144
Issue number6
Publication statusPublished - 5 Feb 2000

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