Novel understanding on thoracic aortic diseases from bioengineering concepts

T. M.J. Van Bakel, F. J.H. Nauta, Michele Conti, Rodrigo Romarowski, Simone Morganti, J. A. Van Herwaarden, C. Alberto Figueroa, F. Auricchio, Santi Trimarchi*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Abstract

Endovascular treatment modalities have decreased the mortality and morbidity of thoracic aortic diseases considerably in the past decades, due to the effectiveness of such interventions and the minimal invasive character. While endovascular treatment options have become more advanced, preoperative planning and follow-up outcomes are still mainly based on the measurement of the maximum diameter and growth rate of the thoracic aorta on static imaging. These measurements do not take into account the biomechanical aortic behavior over the cardiac cycle and do not visualize hemodynamic changes in blood flow. In this chapter, we evaluate endovascular treatment options from a biomechanical point of view and assess how dynamic imaging and computational modeling may contribute to the understanding of thoracic aortic diseases and aid clinical decision-making.

Original languageEnglish
Title of host publicationSurgical Management of Aortic Pathology
Subtitle of host publicationCurrent Fundamentals for the Clinical Management of Aortic Disease
PublisherSpringer International Publishing AG
Pages141-148
Number of pages8
ISBN (Electronic)9783709148747
ISBN (Print)9783709148723
DOIs
Publication statusPublished - 1 Jan 2019

Keywords

  • Aortic dissection
  • Bioengineering
  • Computational fluid dynamics
  • Finite element analysis
  • TEVAR
  • Thoracic aorta
  • Thoracic aortic aneurysm

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