Novel cyclovirus in human cerebrospinal fluid, Malawi, 2010-2011

Saskia L. Smits; Ed E. Zijlstra; Jaap J. van Hellemond; Claudia M.E. Schapendonk; Rogier Bodewes; Anita Schürch; Bart L. Haagmans; Albert D.M.E. Osterhaus

doi:10.3201/eid1909.130404

Novel cyclovirus in human cerebrospinal fluid, Malawi, 2010-2011

Saskia L. Smits
, Ed E. Zijlstra
, Jaap J. van Hellemond
, Claudia M.E. Schapendonk
, Rogier Bodewes
, Anita Schürch
, Bart L. Haagmans
, Albert D.M.E. Osterhaus

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

To identify unknown human viruses, we analyzed serum and cerebrospinal fluid samples from patients with unexplained paraplegia from Malawi by using viral metagenomics. A novel cyclovirus species was identified and subsequently found in 15% and 10% of serum and cerebrospinal fluid samples, respectively. These data expand our knowledge of cyclovirus diversity and tropism.

Original language	English
Journal	Emerging infectious diseases
Volume	19
Issue number	9
DOIs	https://doi.org/10.3201/eid1909.130404
Publication status	Published - 2013
Externally published	Yes

Keywords

cerebrospinal fluid
cyclovirus
Malawi
Paraplegia
random amplification
serum
virus
viruses

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10.3201/eid1909.130404

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title = "Novel cyclovirus in human cerebrospinal fluid, Malawi, 2010-2011",

abstract = "To identify unknown human viruses, we analyzed serum and cerebrospinal fluid samples from patients with unexplained paraplegia from Malawi by using viral metagenomics. A novel cyclovirus species was identified and subsequently found in 15\% and 10\% of serum and cerebrospinal fluid samples, respectively. These data expand our knowledge of cyclovirus diversity and tropism.",

keywords = "cerebrospinal fluid, cyclovirus, Malawi, Paraplegia, random amplification, serum, virus, viruses",

author = "Smits, \{Saskia L.\} and Zijlstra, \{Ed E.\} and \{van Hellemond\}, \{Jaap J.\} and Schapendonk, \{Claudia M.E.\} and Rogier Bodewes and Anita Sch{\"u}rch and Haagmans, \{Bart L.\} and Osterhaus, \{Albert D.M.E.\}",

year = "2013",

doi = "10.3201/eid1909.130404",

language = "English",

volume = "19",

journal = "Emerging infectious diseases",

issn = "1080-6040",

publisher = "Centers for Disease Control and Prevention (CDC)",

number = "9",

}

TY - JOUR

T1 - Novel cyclovirus in human cerebrospinal fluid, Malawi, 2010-2011

AU - Smits, Saskia L.

AU - Zijlstra, Ed E.

AU - van Hellemond, Jaap J.

AU - Schapendonk, Claudia M.E.

AU - Bodewes, Rogier

AU - Schürch, Anita

AU - Haagmans, Bart L.

AU - Osterhaus, Albert D.M.E.

PY - 2013

Y1 - 2013

N2 - To identify unknown human viruses, we analyzed serum and cerebrospinal fluid samples from patients with unexplained paraplegia from Malawi by using viral metagenomics. A novel cyclovirus species was identified and subsequently found in 15% and 10% of serum and cerebrospinal fluid samples, respectively. These data expand our knowledge of cyclovirus diversity and tropism.

AB - To identify unknown human viruses, we analyzed serum and cerebrospinal fluid samples from patients with unexplained paraplegia from Malawi by using viral metagenomics. A novel cyclovirus species was identified and subsequently found in 15% and 10% of serum and cerebrospinal fluid samples, respectively. These data expand our knowledge of cyclovirus diversity and tropism.

KW - cerebrospinal fluid

KW - cyclovirus

KW - Malawi

KW - Paraplegia

KW - random amplification

KW - serum

KW - virus

KW - viruses

UR - https://www.scopus.com/pages/publications/84896591083

U2 - 10.3201/eid1909.130404

DO - 10.3201/eid1909.130404

M3 - Article

C2 - 23968557

AN - SCOPUS:84896591083

SN - 1080-6040

VL - 19

JO - Emerging infectious diseases

JF - Emerging infectious diseases

IS - 9

ER -

Novel cyclovirus in human cerebrospinal fluid, Malawi, 2010-2011

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Keywords

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