Novel cyclovirus in human cerebrospinal fluid, Malawi, 2010-2011

Saskia L. Smits; Ed E. Zijlstra; Jaap J. van Hellemond; Claudia M.E. Schapendonk; Rogier Bodewes; Anita Schürch; Bart L. Haagmans; Albert D.M.E. Osterhaus

doi:10.3201/eid1909.130404

Novel cyclovirus in human cerebrospinal fluid, Malawi, 2010-2011

Saskia L. Smits, Ed E. Zijlstra, Jaap J. van Hellemond, Claudia M.E. Schapendonk, Rogier Bodewes, Anita Schürch, Bart L. Haagmans, Albert D.M.E. Osterhaus

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

To identify unknown human viruses, we analyzed serum and cerebrospinal fluid samples from patients with unexplained paraplegia from Malawi by using viral metagenomics. A novel cyclovirus species was identified and subsequently found in 15% and 10% of serum and cerebrospinal fluid samples, respectively. These data expand our knowledge of cyclovirus diversity and tropism.

Original language	English
Journal	Emerging infectious diseases
Volume	19
Issue number	9
DOIs	https://doi.org/10.3201/eid1909.130404
Publication status	Published - 2013
Externally published	Yes

Keywords

cerebrospinal fluid
cyclovirus
Malawi
Paraplegia
random amplification
serum
virus
viruses

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10.3201/eid1909.130404

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title = "Novel cyclovirus in human cerebrospinal fluid, Malawi, 2010-2011",

abstract = "To identify unknown human viruses, we analyzed serum and cerebrospinal fluid samples from patients with unexplained paraplegia from Malawi by using viral metagenomics. A novel cyclovirus species was identified and subsequently found in 15% and 10% of serum and cerebrospinal fluid samples, respectively. These data expand our knowledge of cyclovirus diversity and tropism.",

keywords = "cerebrospinal fluid, cyclovirus, Malawi, Paraplegia, random amplification, serum, virus, viruses",

author = "Smits, {Saskia L.} and Zijlstra, {Ed E.} and {van Hellemond}, {Jaap J.} and Schapendonk, {Claudia M.E.} and Rogier Bodewes and Anita Sch{\"u}rch and Haagmans, {Bart L.} and Osterhaus, {Albert D.M.E.}",

year = "2013",

doi = "10.3201/eid1909.130404",

language = "English",

volume = "19",

journal = "Emerging infectious diseases",

issn = "1080-6040",

publisher = "Centers for Disease Control and Prevention (CDC)",

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TY - JOUR

T1 - Novel cyclovirus in human cerebrospinal fluid, Malawi, 2010-2011

AU - Smits, Saskia L.

AU - Zijlstra, Ed E.

AU - van Hellemond, Jaap J.

AU - Schapendonk, Claudia M.E.

AU - Bodewes, Rogier

AU - Schürch, Anita

AU - Haagmans, Bart L.

AU - Osterhaus, Albert D.M.E.

PY - 2013

Y1 - 2013

N2 - To identify unknown human viruses, we analyzed serum and cerebrospinal fluid samples from patients with unexplained paraplegia from Malawi by using viral metagenomics. A novel cyclovirus species was identified and subsequently found in 15% and 10% of serum and cerebrospinal fluid samples, respectively. These data expand our knowledge of cyclovirus diversity and tropism.

AB - To identify unknown human viruses, we analyzed serum and cerebrospinal fluid samples from patients with unexplained paraplegia from Malawi by using viral metagenomics. A novel cyclovirus species was identified and subsequently found in 15% and 10% of serum and cerebrospinal fluid samples, respectively. These data expand our knowledge of cyclovirus diversity and tropism.

KW - cerebrospinal fluid

KW - cyclovirus

KW - Malawi

KW - Paraplegia

KW - random amplification

KW - serum

KW - virus

KW - viruses

UR - http://www.scopus.com/inward/record.url?scp=84896591083&partnerID=8YFLogxK

U2 - 10.3201/eid1909.130404

DO - 10.3201/eid1909.130404

M3 - Article

C2 - 23968557

AN - SCOPUS:84896591083

SN - 1080-6040

VL - 19

JO - Emerging infectious diseases

JF - Emerging infectious diseases

IS - 9

ER -

Novel cyclovirus in human cerebrospinal fluid, Malawi, 2010-2011

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Keywords

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