Non-invasive imaging assessment in angina with non-obstructive coronary arteries (ANOCA)

Luca Bergamaschi; Antonio De Vita; Angelo Villano; Saverio Tremamunno; Matteo Armillotta; Francesco Angeli; Marta Belmonte; Pasquale Paolisso; Alberto Foà; Emanuele Gallinoro; Alberto Polimeni; Vincenzo Sucato; Doralisa Morrone; Domenico Tuttolomondo; Anna Giulia Pavon; Marco Guglielmo; Nicola Gaibazzi; Saima Mushtaq; Pasquale Perrone Filardi; Ciro Indolfi; Eugenio Picano; Gianluca Pontone; Gaetano Antonio Lanza; Carmine Pizzi

doi:10.1016/j.cpcardiol.2025.103021

Non-invasive imaging assessment in angina with non-obstructive coronary arteries (ANOCA)

Luca Bergamaschi, Antonio De Vita, Angelo Villano, Saverio Tremamunno, Matteo Armillotta, Francesco Angeli, Marta Belmonte, Pasquale Paolisso, Alberto Foà, Emanuele Gallinoro, Alberto Polimeni, Vincenzo Sucato, Doralisa Morrone, Domenico Tuttolomondo, Anna Giulia Pavon, Marco Guglielmo, Nicola Gaibazzi, Saima Mushtaq, Pasquale Perrone Filardi, Ciro IndolfiEugenio Picano, Gianluca Pontone, Gaetano Antonio Lanza, Carmine Pizzi,

Research output: Contribution to journal › Review article › peer-review

Abstract

Due to its significant prevalence and clinical implications, angina with non-obstructive coronary arteries (ANOCA) has become a major focus in modern cardiology. In fact, diagnosing ANOCA presents a significant challenge. The final diagnosis is often difficult, delayed, and frequently necessitates an invasive assessment through coronary angiography. However, recent improvements in non-invasive cardiac imaging allow a diagnosis of ANOCA using a combination of clinical evaluation, anatomical coronary imaging, and functional testing. This narrative review aims to critically assess various non-invasive diagnostic methods and propose a multimodal approach to diagnose ANOCA and tailor appropriate treatments.

Original language	English
Article number	103021
Number of pages	10
Journal	Current problems in cardiology
Volume	50
Issue number	5
Early online date	25 Feb 2025
DOIs	https://doi.org/10.1016/j.cpcardiol.2025.103021
Publication status	E-pub ahead of print - 25 Feb 2025

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10.1016/j.cpcardiol.2025.103021Licence: CC BY

1-s2.0-S0146280625000441-mainFinal published version, 1.45 MBLicence: CC BY

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Bergamaschi, L., De Vita, A., Villano, A., Tremamunno, S., Armillotta, M., Angeli, F., Belmonte, M., Paolisso, P., Foà, A., Gallinoro, E., Polimeni, A., Sucato, V., Morrone, D., Tuttolomondo, D., Pavon, A. G., Guglielmo, M., Gaibazzi, N., Mushtaq, S., Filardi, P. P. (2025). Non-invasive imaging assessment in angina with non-obstructive coronary arteries (ANOCA). Current problems in cardiology, 50(5), Article 103021. Advance online publication. https://doi.org/10.1016/j.cpcardiol.2025.103021

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title = "Non-invasive imaging assessment in angina with non-obstructive coronary arteries (ANOCA)",

abstract = "Due to its significant prevalence and clinical implications, angina with non-obstructive coronary arteries (ANOCA) has become a major focus in modern cardiology. In fact, diagnosing ANOCA presents a significant challenge. The final diagnosis is often difficult, delayed, and frequently necessitates an invasive assessment through coronary angiography. However, recent improvements in non-invasive cardiac imaging allow a diagnosis of ANOCA using a combination of clinical evaluation, anatomical coronary imaging, and functional testing. This narrative review aims to critically assess various non-invasive diagnostic methods and propose a multimodal approach to diagnose ANOCA and tailor appropriate treatments.",

author = "Luca Bergamaschi and {De Vita}, Antonio and Angelo Villano and Saverio Tremamunno and Matteo Armillotta and Francesco Angeli and Marta Belmonte and Pasquale Paolisso and Alberto Fo{\`a} and Emanuele Gallinoro and Alberto Polimeni and Vincenzo Sucato and Doralisa Morrone and Domenico Tuttolomondo and Pavon, {Anna Giulia} and Marco Guglielmo and Nicola Gaibazzi and Saima Mushtaq and Filardi, {Pasquale Perrone} and Ciro Indolfi and Eugenio Picano and Gianluca Pontone and Lanza, {Gaetano Antonio} and Carmine Pizzi",

note = "Copyright {\textcopyright} 2025. Published by Elsevier Inc.",

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language = "English",

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Bergamaschi, L, De Vita, A, Villano, A, Tremamunno, S, Armillotta, M, Angeli, F, Belmonte, M, Paolisso, P, Foà, A, Gallinoro, E, Polimeni, A, Sucato, V, Morrone, D, Tuttolomondo, D, Pavon, AG, Guglielmo, M, Gaibazzi, N, Mushtaq, S, Filardi, PP, Indolfi, C, Picano, E, Pontone, G, Lanza, GA, Pizzi, C 2025, 'Non-invasive imaging assessment in angina with non-obstructive coronary arteries (ANOCA)', Current problems in cardiology, vol. 50, no. 5, 103021. https://doi.org/10.1016/j.cpcardiol.2025.103021

TY - JOUR

T1 - Non-invasive imaging assessment in angina with non-obstructive coronary arteries (ANOCA)

AU - Bergamaschi, Luca

AU - De Vita, Antonio

AU - Villano, Angelo

AU - Tremamunno, Saverio

AU - Armillotta, Matteo

AU - Angeli, Francesco

AU - Belmonte, Marta

AU - Paolisso, Pasquale

AU - Foà, Alberto

AU - Gallinoro, Emanuele

AU - Polimeni, Alberto

AU - Sucato, Vincenzo

AU - Morrone, Doralisa

AU - Tuttolomondo, Domenico

AU - Pavon, Anna Giulia

AU - Guglielmo, Marco

AU - Gaibazzi, Nicola

AU - Mushtaq, Saima

AU - Filardi, Pasquale Perrone

AU - Indolfi, Ciro

AU - Picano, Eugenio

AU - Pontone, Gianluca

AU - Lanza, Gaetano Antonio

AU - Pizzi, Carmine

PY - 2025/2/25

Y1 - 2025/2/25

N2 - Due to its significant prevalence and clinical implications, angina with non-obstructive coronary arteries (ANOCA) has become a major focus in modern cardiology. In fact, diagnosing ANOCA presents a significant challenge. The final diagnosis is often difficult, delayed, and frequently necessitates an invasive assessment through coronary angiography. However, recent improvements in non-invasive cardiac imaging allow a diagnosis of ANOCA using a combination of clinical evaluation, anatomical coronary imaging, and functional testing. This narrative review aims to critically assess various non-invasive diagnostic methods and propose a multimodal approach to diagnose ANOCA and tailor appropriate treatments.

AB - Due to its significant prevalence and clinical implications, angina with non-obstructive coronary arteries (ANOCA) has become a major focus in modern cardiology. In fact, diagnosing ANOCA presents a significant challenge. The final diagnosis is often difficult, delayed, and frequently necessitates an invasive assessment through coronary angiography. However, recent improvements in non-invasive cardiac imaging allow a diagnosis of ANOCA using a combination of clinical evaluation, anatomical coronary imaging, and functional testing. This narrative review aims to critically assess various non-invasive diagnostic methods and propose a multimodal approach to diagnose ANOCA and tailor appropriate treatments.

U2 - 10.1016/j.cpcardiol.2025.103021

DO - 10.1016/j.cpcardiol.2025.103021

M3 - Review article

C2 - 40015352

SN - 0146-2806

VL - 50

JO - Current problems in cardiology

JF - Current problems in cardiology

IS - 5

M1 - 103021

ER -

Non-invasive imaging assessment in angina with non-obstructive coronary arteries (ANOCA)

Abstract

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