No association between RFLPs at the porphobilinogen deaminase gene and schizophrenia

M. J. Owen; R. Mant; E. Parfitt; J. Williams; P. Asherson; G. O'Mahoney; J. Van Os; D. Llewellyn; D. Collier; M. Gill; P. McGuffin

doi:10.1007/BF00210756

No association between RFLPs at the porphobilinogen deaminase gene and schizophrenia

M. J. Owen^*
, R. Mant
, E. Parfitt
, J. Williams
, P. Asherson
, G. O'Mahoney
, J. Van Os
, D. Llewellyn
, D. Collier
, M. Gill
, P. McGuffin

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

12 Citations (Scopus)

Abstract

An association study of restriction fragment length polymorphisms (RFLPs) in the porphobilinogen deaminase (PBGD) gene and schizophrenia was conducted. RFLPs detected by MspI, PstI, ApaLI and BstNI in intron 1 of the gene were studied in 49 patients and 79 controls. There were no significant differences between the groups in allele frequencies, genotype counts or haplotype distribution.

Original language	English
Pages (from-to)	131-132
Number of pages	2
Journal	Human Genetics
Volume	90
Issue number	1-2
DOIs	https://doi.org/10.1007/BF00210756
Publication status	Published - Sept 1992
Externally published	Yes

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10.1007/BF00210756

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title = "No association between RFLPs at the porphobilinogen deaminase gene and schizophrenia",

abstract = "An association study of restriction fragment length polymorphisms (RFLPs) in the porphobilinogen deaminase (PBGD) gene and schizophrenia was conducted. RFLPs detected by MspI, PstI, ApaLI and BstNI in intron 1 of the gene were studied in 49 patients and 79 controls. There were no significant differences between the groups in allele frequencies, genotype counts or haplotype distribution.",

author = "Owen, \{M. J.\} and R. Mant and E. Parfitt and J. Williams and P. Asherson and G. O'Mahoney and \{Van Os\}, J. and D. Llewellyn and D. Collier and M. Gill and P. McGuffin",

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TY - JOUR

T1 - No association between RFLPs at the porphobilinogen deaminase gene and schizophrenia

AU - Owen, M. J.

AU - Mant, R.

AU - Parfitt, E.

AU - Williams, J.

AU - Asherson, P.

AU - O'Mahoney, G.

AU - Van Os, J.

AU - Llewellyn, D.

AU - Collier, D.

AU - Gill, M.

AU - McGuffin, P.

PY - 1992/9

Y1 - 1992/9

N2 - An association study of restriction fragment length polymorphisms (RFLPs) in the porphobilinogen deaminase (PBGD) gene and schizophrenia was conducted. RFLPs detected by MspI, PstI, ApaLI and BstNI in intron 1 of the gene were studied in 49 patients and 79 controls. There were no significant differences between the groups in allele frequencies, genotype counts or haplotype distribution.

AB - An association study of restriction fragment length polymorphisms (RFLPs) in the porphobilinogen deaminase (PBGD) gene and schizophrenia was conducted. RFLPs detected by MspI, PstI, ApaLI and BstNI in intron 1 of the gene were studied in 49 patients and 79 controls. There were no significant differences between the groups in allele frequencies, genotype counts or haplotype distribution.

UR - https://www.scopus.com/pages/publications/0026785313

U2 - 10.1007/BF00210756

DO - 10.1007/BF00210756

M3 - Article

C2 - 1358782

AN - SCOPUS:0026785313

SN - 0340-6717

VL - 90

SP - 131

EP - 132

JO - Human Genetics

JF - Human Genetics

IS - 1-2

ER -

No association between RFLPs at the porphobilinogen deaminase gene and schizophrenia

Abstract

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