Abstract
Three new drugs that augment the effect of incretins have recently been approved for the treatment of type 2 diabetes.Incretins are intestinal hormones that increase the level of insu-ilin and decrease the level of glucagon. Two of these drugs, sita- gliptin and vildagliptin, are administered orally and have been approved for combination therapy with other oral antihypergly- Jcaemic agents. The third drug, exenatide, is administered parenteral and may be an alternative to insulin if oral agents are 1 inadequately effective. Although these agents have less effect than existing drugs, they are an option if existing drugs are not tolerated or are contraindicated. Currently too little is known about the side-effects of these drugs to determine their place in the treatment of type 2 diabetes.
| Translated title of the contribution | New drugs for type 2 diabete mellitus Huisarts wet |
|---|---|
| Original language | Dutch |
| Pages (from-to) | 233-235 |
| Number of pages | 3 |
| Journal | Huisarts en Wetenschap |
| Volume | 52 |
| Issue number | 5 |
| Publication status | Published - May 2009 |