National Protocol for Model-Based Selection for Proton Therapy in Head and Neck Cancer

  • Johannes A Langendijk
  • , Frank J P Hoebers
  • , Martin A de Jong
  • , Patricia Doornaert
  • , Chris H J Terhaard
  • , Roel J H M Steenbakkers
  • , Olga Hamming-Vrieze
  • , Jeroen B van de Kamer
  • , Wilko F A R Verbakel
  • , Fatma Keskin-Cambay
  • , Johannes B Reitsma
  • , Arjen van der Schaaf
  • , Liesbeth J Boersma
  • , Ewoud Schuit

Research output: Contribution to journalArticleAcademicpeer-review

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Abstract

In the Netherlands, the model-based approach is used to identify patients with head and neck cancer who may benefit most from proton therapy in terms of prevention of late radiation-induced side effects in comparison with photon therapy. To this purpose, a National Indication Protocol Proton therapy for Head and Neck Cancer patients (NIPP-HNC) was developed, which has been approved by the health care authorities. When patients qualify according to the guidelines of the NIPP-HNC, proton therapy is fully reimbursed. This article describes the procedures that were followed to develop this NIPP-HNC and provides all necessary information to introduce model-based selection for patients with head and neck cancer into routine clinical practice.

Original languageEnglish
Pages (from-to)354-365
Number of pages12
JournalInternational journal of particle therapy
Volume8
Issue number1
DOIs
Publication statusPublished - 1 Jun 2021

Keywords

  • head and neck cancer
  • model-based selection
  • national indication protocol
  • proton therapy
  • radiation-induced side effects
  • Radiation-induced side effects
  • Model-based selection
  • National indication protocol
  • Head and neck cancer
  • Proton therapy

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