NADPH:O2 oxidoreductase of human eosinophils in the cell-free system

Ben G J M Bolscher; Leo Koenderman; Anton T J Tool; Petra M. Stokman; Dirk Roos

doi:10.1016/0014-5793(90)81025-J

NADPH:O₂ oxidoreductase of human eosinophils in the cell-free system

Ben G J M Bolscher, Leo Koenderman, Anton T J Tool, Petra M. Stokman, Dirk Roos^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

16 Citations (Scopus)

Abstract

The NADPH oxidase of human eosinophils, measured in the cell-free system, shows the same characteristics as the enzyme from human neutrophils. All proteins required for activity of the enzyme are expressed in eosinophils at a higher level than in neutrophils. Eosinophils isolated from patients with chronic granulomatous disease show the same molecular defects as the neutrophils fom these patients.

Original language	English
Pages (from-to)	269-273
Number of pages	5
Journal	FEBS letters
Volume	268
Issue number	1
DOIs	https://doi.org/10.1016/0014-5793(90)81025-J
Publication status	Published - 30 Jul 1990

Keywords

Cell-free system
Eosinophil
NADPH oxidase

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10.1016/0014-5793(90)81025-J

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abstract = "The NADPH oxidase of human eosinophils, measured in the cell-free system, shows the same characteristics as the enzyme from human neutrophils. All proteins required for activity of the enzyme are expressed in eosinophils at a higher level than in neutrophils. Eosinophils isolated from patients with chronic granulomatous disease show the same molecular defects as the neutrophils fom these patients.",

keywords = "Cell-free system, Eosinophil, NADPH oxidase",

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AU - Tool, Anton T J

AU - Stokman, Petra M.

AU - Roos, Dirk

PY - 1990/7/30

Y1 - 1990/7/30

N2 - The NADPH oxidase of human eosinophils, measured in the cell-free system, shows the same characteristics as the enzyme from human neutrophils. All proteins required for activity of the enzyme are expressed in eosinophils at a higher level than in neutrophils. Eosinophils isolated from patients with chronic granulomatous disease show the same molecular defects as the neutrophils fom these patients.

AB - The NADPH oxidase of human eosinophils, measured in the cell-free system, shows the same characteristics as the enzyme from human neutrophils. All proteins required for activity of the enzyme are expressed in eosinophils at a higher level than in neutrophils. Eosinophils isolated from patients with chronic granulomatous disease show the same molecular defects as the neutrophils fom these patients.

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KW - NADPH oxidase

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ER -

NADPH:O₂ oxidoreductase of human eosinophils in the cell-free system

Abstract

Keywords

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