Mycobacterium avium-infectie bij HIV-geinfecteerde patienten: Epidemiologie, diagnose, profylaxe en behandeling

M. M.E. Schneider; P. Reiss; J. C.C. Borleffs; M. Rozenberg-Arska; I. M. Hoepelman

Mycobacterium avium-infectie bij HIV-geinfecteerde patienten: Epidemiologie, diagnose, profylaxe en behandeling

Translated title of the contribution: Mycobacterium avium infection in HIV-infected patients: Epidemiology, diagnosis, prophylaxis and treatment

M. M.E. Schneider^*, P. Reiss, J. C.C. Borleffs, M. Rozenberg-Arska, I. M. Hoepelman

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

7 Citations (Scopus)

Abstract

- The prevalence of infection with Mycobacterium avium complex (MAC) has increased since the outbreak of the HIV pandemic. This complex comprises two organisms: M. avium (mostly) and M. intracellulare (rarely). The source of MAC infection is not known. - The principal risk factors for disseminated MAC infection in a patient with HIV infection are a low CD ₄ count and a previous opportunistic infection. - The symptoms of disseminated MAC infection resemble those of HIV wasting: A positive culture of normally sterile tissue confirms a MAC infection. - There is reserve with regard to routine prophylaxis in HIV-infected persons because of the possible development of resistance, interaction with other drugs used in AIDS, toxicity and possible absorption disorders which might cause prophylaxis to fail. - For the treatment of disseminated MAC infection, a combination of at least two medicaments (macrolides and ethambutol) is recommended.

Translated title of the contribution	Mycobacterium avium infection in HIV-infected patients: Epidemiology, diagnosis, prophylaxis and treatment
Original language	Dutch
Pages (from-to)	80-83
Number of pages	4
Journal	Nederlands Tijdschrift voor Geneeskunde
Volume	141
Issue number	2
Publication status	Published - 4 Feb 1997

Cite this

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title = "Mycobacterium avium-infectie bij HIV-geinfecteerde patienten: Epidemiologie, diagnose, profylaxe en behandeling",

abstract = "- The prevalence of infection with Mycobacterium avium complex (MAC) has increased since the outbreak of the HIV pandemic. This complex comprises two organisms: M. avium (mostly) and M. intracellulare (rarely). The source of MAC infection is not known. - The principal risk factors for disseminated MAC infection in a patient with HIV infection are a low CD 4 count and a previous opportunistic infection. - The symptoms of disseminated MAC infection resemble those of HIV wasting: A positive culture of normally sterile tissue confirms a MAC infection. - There is reserve with regard to routine prophylaxis in HIV-infected persons because of the possible development of resistance, interaction with other drugs used in AIDS, toxicity and possible absorption disorders which might cause prophylaxis to fail. - For the treatment of disseminated MAC infection, a combination of at least two medicaments (macrolides and ethambutol) is recommended.",

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AU - Borleffs, J. C.C.

AU - Rozenberg-Arska, M.

AU - Hoepelman, I. M.

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Mycobacterium avium-infectie bij HIV-geinfecteerde patienten: Epidemiologie, diagnose, profylaxe en behandeling

Abstract

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