Multifocale lymphangio-endotheliomatose met trombocytopenie (MLE-T): vroegtijdige herkenning is van levensbelang

M. N. Van Der Horst; J.H. Sillevis-Smitt; M. A.D. Peters; M. A. Middelkamp Hup; L. Van Den Berg; R. Wösten-Van Asperen; A. Kindermann; J. H.M. Merks

Multifocale lymphangio-endotheliomatose met trombocytopenie (MLE-T): vroegtijdige herkenning is van levensbelang

M. N. Van Der Horst^*
, J.H. Sillevis-Smitt
, M. A.D. Peters
, M. A. Middelkamp Hup
, L. Van Den Berg
, R. Wösten-Van Asperen
, A. Kindermann
, J. H.M. Merks

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Multifocal lymphangio-endotheliomatosis with thrombocytopenia (MLE-T) is an extremely rare disease and manifests itself with diffuse vascular cutaneous and gastrointestinal tract lesions, which can cause severe bleeding. The thrombocytopenia is chronic and fluctuating and thought to result from platelet trapping by the multifocal vascular lesions. We describe a newborn with numerous cutaneous and extracutaneous lesions who was successfully treated with thalidomide.

Original language	Dutch
Pages (from-to)	314-317
Number of pages	4
Journal	Nederlands Tijdschrift voor Dermatologie & Venereologie
Volume	26
Issue number	5
Publication status	Published - 1 May 2016

Keywords

Congenital vascular disease
Diffuse neonatal hemangiomatosis
MLE-T
MLT
Multifocal lymphangio-endotheliomatosis and thrombocytopenia
Thalidomide

Cite this

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title = "Multifocale lymphangio-endotheliomatose met trombocytopenie (MLE-T): vroegtijdige herkenning is van levensbelang",

abstract = "Multifocal lymphangio-endotheliomatosis with thrombocytopenia (MLE-T) is an extremely rare disease and manifests itself with diffuse vascular cutaneous and gastrointestinal tract lesions, which can cause severe bleeding. The thrombocytopenia is chronic and fluctuating and thought to result from platelet trapping by the multifocal vascular lesions. We describe a newborn with numerous cutaneous and extracutaneous lesions who was successfully treated with thalidomide.",

keywords = "Congenital vascular disease, Diffuse neonatal hemangiomatosis, MLE-T, MLT, Multifocal lymphangio-endotheliomatosis and thrombocytopenia, Thalidomide",

author = "\{Van Der Horst\}, \{M. N.\} and J.H. Sillevis-Smitt and Peters, \{M. A.D.\} and \{Middelkamp Hup\}, \{M. A.\} and \{Van Den Berg\}, L. and \{W{\"o}sten-Van Asperen\}, R. and A. Kindermann and Merks, \{J. H.M.\}",

year = "2016",

month = may,

day = "1",

language = "Dutch",

volume = "26",

pages = "314--317",

journal = "Nederlands Tijdschrift voor Dermatologie \& Venereologie",

issn = "0925-8604",

publisher = "Stichting Beheer Tijdschriften Dermatologie",

number = "5",

}

TY - JOUR

T1 - Multifocale lymphangio-endotheliomatose met trombocytopenie (MLE-T)

T2 - vroegtijdige herkenning is van levensbelang

AU - Van Der Horst, M. N.

AU - Sillevis-Smitt, J.H.

AU - Peters, M. A.D.

AU - Middelkamp Hup, M. A.

AU - Van Den Berg, L.

AU - Wösten-Van Asperen, R.

AU - Kindermann, A.

AU - Merks, J. H.M.

PY - 2016/5/1

Y1 - 2016/5/1

N2 - Multifocal lymphangio-endotheliomatosis with thrombocytopenia (MLE-T) is an extremely rare disease and manifests itself with diffuse vascular cutaneous and gastrointestinal tract lesions, which can cause severe bleeding. The thrombocytopenia is chronic and fluctuating and thought to result from platelet trapping by the multifocal vascular lesions. We describe a newborn with numerous cutaneous and extracutaneous lesions who was successfully treated with thalidomide.

AB - Multifocal lymphangio-endotheliomatosis with thrombocytopenia (MLE-T) is an extremely rare disease and manifests itself with diffuse vascular cutaneous and gastrointestinal tract lesions, which can cause severe bleeding. The thrombocytopenia is chronic and fluctuating and thought to result from platelet trapping by the multifocal vascular lesions. We describe a newborn with numerous cutaneous and extracutaneous lesions who was successfully treated with thalidomide.

KW - Congenital vascular disease

KW - Diffuse neonatal hemangiomatosis

KW - MLE-T

KW - MLT

KW - Multifocal lymphangio-endotheliomatosis and thrombocytopenia

KW - Thalidomide

UR - https://www.scopus.com/pages/publications/85029509659

M3 - Article

AN - SCOPUS:85029509659

SN - 0925-8604

VL - 26

SP - 314

EP - 317

JO - Nederlands Tijdschrift voor Dermatologie & Venereologie

JF - Nederlands Tijdschrift voor Dermatologie & Venereologie

IS - 5

ER -

Multifocale lymphangio-endotheliomatose met trombocytopenie (MLE-T): vroegtijdige herkenning is van levensbelang

Abstract

Keywords

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