TY - JOUR
T1 - Multidisciplinary Tinnitus Research
T2 - Challenges and Future Directions From the Perspective of Early Stage Researchers
AU - Simoes, Jorge Piano
AU - Daoud, Elza
AU - Shabbir, Maryam
AU - Amanat, Sana
AU - Assouly, Kelly
AU - Biswas, Roshni
AU - Casolani, Chiara
AU - Dode, Albi
AU - Enzler, Falco
AU - Jacquemin, Laure
AU - Joergensen, Mie
AU - Kok, Tori
AU - Liyanage, Nuwan
AU - Lourenco, Matheus
AU - Makani, Punitkumar
AU - Mehdi, Muntazir
AU - Ramadhani, Anissa L.
AU - Riha, Constanze
AU - Santacruz, Jose Lopez
AU - Schiller, Axel
AU - Schoisswohl, Stefan
AU - Trpchevska, Natalia
AU - Genitsaridi, Eleni
N1 - Funding Information:
Funding. This project has received funding from the European Union's Horizon 2020 research and innovation program under the Marie Sklodowska-Curie grant agreements number 722046, 764604, and 848261.
Funding Information:
This project has received funding from the European Union’s Horizon 2020 research and innovation program under the Marie Sklodowska-Curie grant agreements number 722046, 764604, and 848261.
Publisher Copyright:
© Copyright © 2021 Simoes, Daoud, Shabbir, Amanat, Assouly, Biswas, Casolani, Dode, Enzler, Jacquemin, Joergensen, Kok, Liyanage, Lourenco, Makani, Mehdi, Ramadhani, Riha, Santacruz, Schiller, Schoisswohl, Trpchevska and Genitsaridi.
PY - 2021/6/11
Y1 - 2021/6/11
N2 - Tinnitus can be a burdensome condition on both individual and societal levels. Many aspects of this condition remain elusive, including its underlying mechanisms, ultimately hindering the development of a cure. Interdisciplinary approaches are required to overcome long-established research challenges. This review summarizes current knowledge in various tinnitus-relevant research fields including tinnitus generating mechanisms, heterogeneity, epidemiology, assessment, and treatment development, in an effort to highlight the main challenges and provide suggestions for future research to overcome them. Four common themes across different areas were identified as future research direction: (1) Further establishment of multicenter and multidisciplinary collaborations; (2) Systematic reviews and syntheses of existing knowledge; (3) Standardization of research methods including tinnitus assessment, data acquisition, and data analysis protocols; (4) The design of studies with large sample sizes and the creation of large tinnitus-specific databases that would allow in-depth exploration of tinnitus heterogeneity.
AB - Tinnitus can be a burdensome condition on both individual and societal levels. Many aspects of this condition remain elusive, including its underlying mechanisms, ultimately hindering the development of a cure. Interdisciplinary approaches are required to overcome long-established research challenges. This review summarizes current knowledge in various tinnitus-relevant research fields including tinnitus generating mechanisms, heterogeneity, epidemiology, assessment, and treatment development, in an effort to highlight the main challenges and provide suggestions for future research to overcome them. Four common themes across different areas were identified as future research direction: (1) Further establishment of multicenter and multidisciplinary collaborations; (2) Systematic reviews and syntheses of existing knowledge; (3) Standardization of research methods including tinnitus assessment, data acquisition, and data analysis protocols; (4) The design of studies with large sample sizes and the creation of large tinnitus-specific databases that would allow in-depth exploration of tinnitus heterogeneity.
KW - big data
KW - heterogeneity
KW - interdisciplinary collaborations
KW - review
KW - standardization
KW - tinnitus
KW - treatment development
UR - https://www.scopus.com/pages/publications/85108890915
U2 - 10.3389/fnagi.2021.647285
DO - 10.3389/fnagi.2021.647285
M3 - Review article
AN - SCOPUS:85108890915
SN - 1663-4365
VL - 13
SP - 1
EP - 24
JO - Frontiers in Aging Neuroscience
JF - Frontiers in Aging Neuroscience
M1 - 647285
ER -