MR Angiography of Collateral Arteries in a Hind Limb Ischemia Model: Comparison between Blood Pool Agent Gadomer and Small Contrast Agent Gd-DTPA

Karolien Jaspers; Bas Versluis; Tim Leiner; Petra Dijkstra; Marlies Oostendorp; Jolanda M. van Golde; Mark J. Post; Walter H. Backes

doi:10.1371/journal.pone.0016159

MR Angiography of Collateral Arteries in a Hind Limb Ischemia Model: Comparison between Blood Pool Agent Gadomer and Small Contrast Agent Gd-DTPA

Karolien Jaspers^*
, Bas Versluis
, Tim Leiner
, Petra Dijkstra
, Marlies Oostendorp
, Jolanda M. van Golde
, Mark J. Post
, Walter H. Backes

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

The objective of this study was to compare the blood pool agent Gadomer with a small contrast agent for the visualization of ultra-small, collateral arteries (diameter0.10). Inter-observer variation was 24% and 18% for Gadomer and Gd-DTPA, respectively. In conclusion, blood pool agent Gadomer improved vessel conspicuity compared to Gd-DTPA. Steady-state MRA can be considered as an excellent non-invasive alternative to intra-arterial XRA for the visualization of ultra-small collateral arteries.

Original language	English
Article number	16159
Number of pages	6
Journal	PLoS ONE [E]
Volume	6
Issue number	1
DOIs	https://doi.org/10.1371/journal.pone.0016159
Publication status	Published - 26 Jan 2011

Keywords

MAGNETIC-RESONANCE ANGIOGRAPHY
GADOFOSVESET TRISODIUM
P792
ARTERIOGENESIS
VESSELS
DISEASE
GROWTH

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abstract = "The objective of this study was to compare the blood pool agent Gadomer with a small contrast agent for the visualization of ultra-small, collateral arteries (diameter0.10). Inter-observer variation was 24\% and 18\% for Gadomer and Gd-DTPA, respectively. In conclusion, blood pool agent Gadomer improved vessel conspicuity compared to Gd-DTPA. Steady-state MRA can be considered as an excellent non-invasive alternative to intra-arterial XRA for the visualization of ultra-small collateral arteries.",

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AU - Jaspers, Karolien

AU - Versluis, Bas

AU - Leiner, Tim

AU - Dijkstra, Petra

AU - Oostendorp, Marlies

AU - van Golde, Jolanda M.

AU - Post, Mark J.

AU - Backes, Walter H.

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AB - The objective of this study was to compare the blood pool agent Gadomer with a small contrast agent for the visualization of ultra-small, collateral arteries (diameter0.10). Inter-observer variation was 24% and 18% for Gadomer and Gd-DTPA, respectively. In conclusion, blood pool agent Gadomer improved vessel conspicuity compared to Gd-DTPA. Steady-state MRA can be considered as an excellent non-invasive alternative to intra-arterial XRA for the visualization of ultra-small collateral arteries.

KW - MAGNETIC-RESONANCE ANGIOGRAPHY

KW - GADOFOSVESET TRISODIUM

KW - P792

KW - ARTERIOGENESIS

KW - VESSELS

KW - DISEASE

KW - GROWTH

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ER -

MR Angiography of Collateral Arteries in a Hind Limb Ischemia Model: Comparison between Blood Pool Agent Gadomer and Small Contrast Agent Gd-DTPA

Abstract

Keywords

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