Monitoring cerebral oxygenation of the immature brain: a neuroprotective strategy?

Frank van Bel; Jonathan P Mintzer

doi:10.1038/s41390-018-0026-8

Monitoring cerebral oxygenation of the immature brain: a neuroprotective strategy?

Frank van Bel^*
, Jonathan P Mintzer

^*Corresponding author for this work

Birth Center Neonatology - Medical

Research output: Contribution to journal › Review article › peer-review

Abstract

Monitoring of cerebral oxygenation (rScO2) with near-infrared spectroscopy (NIRS) is a feasible noninvasive bedside technique in the NICU. This review discusses the possible neuroprotective role of "pattern recognition" of NIRS-derived rScO2 in preterm neonates with regard to the prevention of severe intraventricular hemorrhage and hypoxia/hyperoxia-related white matter injury. This neuroprotective role of rScO2 monitoring is discussed as a modality to aid in the early detection of cerebral oxygenation conditions predisposing to these complications. Practical guidelines are provided concerning management of abnormal rScO2 patterns as well as a brief discussion concerning the need for international consensus and the legal aspects associated with the introduction of a new NICU bedside monitoring strategy.

Original language	English
Pages (from-to)	159-164
Number of pages	6
Journal	Pediatric Research
Volume	84
Issue number	2
DOIs	https://doi.org/10.1038/s41390-018-0026-8
Publication status	Published - 1 Aug 2018

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10.1038/s41390-018-0026-8

s41390-018-0026-8Final published version, 1.15 MBLicence: Taverne

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title = "Monitoring cerebral oxygenation of the immature brain: a neuroprotective strategy?",

abstract = "Monitoring of cerebral oxygenation (rScO2) with near-infrared spectroscopy (NIRS) is a feasible noninvasive bedside technique in the NICU. This review discusses the possible neuroprotective role of {"}pattern recognition{"} of NIRS-derived rScO2 in preterm neonates with regard to the prevention of severe intraventricular hemorrhage and hypoxia/hyperoxia-related white matter injury. This neuroprotective role of rScO2 monitoring is discussed as a modality to aid in the early detection of cerebral oxygenation conditions predisposing to these complications. Practical guidelines are provided concerning management of abnormal rScO2 patterns as well as a brief discussion concerning the need for international consensus and the legal aspects associated with the introduction of a new NICU bedside monitoring strategy.",

author = "\{van Bel\}, Frank and Mintzer, \{Jonathan P\}",

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doi = "10.1038/s41390-018-0026-8",

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T2 - a neuroprotective strategy?

AU - van Bel, Frank

AU - Mintzer, Jonathan P

PY - 2018/8/1

Y1 - 2018/8/1

N2 - Monitoring of cerebral oxygenation (rScO2) with near-infrared spectroscopy (NIRS) is a feasible noninvasive bedside technique in the NICU. This review discusses the possible neuroprotective role of "pattern recognition" of NIRS-derived rScO2 in preterm neonates with regard to the prevention of severe intraventricular hemorrhage and hypoxia/hyperoxia-related white matter injury. This neuroprotective role of rScO2 monitoring is discussed as a modality to aid in the early detection of cerebral oxygenation conditions predisposing to these complications. Practical guidelines are provided concerning management of abnormal rScO2 patterns as well as a brief discussion concerning the need for international consensus and the legal aspects associated with the introduction of a new NICU bedside monitoring strategy.

AB - Monitoring of cerebral oxygenation (rScO2) with near-infrared spectroscopy (NIRS) is a feasible noninvasive bedside technique in the NICU. This review discusses the possible neuroprotective role of "pattern recognition" of NIRS-derived rScO2 in preterm neonates with regard to the prevention of severe intraventricular hemorrhage and hypoxia/hyperoxia-related white matter injury. This neuroprotective role of rScO2 monitoring is discussed as a modality to aid in the early detection of cerebral oxygenation conditions predisposing to these complications. Practical guidelines are provided concerning management of abnormal rScO2 patterns as well as a brief discussion concerning the need for international consensus and the legal aspects associated with the introduction of a new NICU bedside monitoring strategy.

UR - https://www.scopus.com/pages/publications/85048574417

U2 - 10.1038/s41390-018-0026-8

DO - 10.1038/s41390-018-0026-8

M3 - Review article

C2 - 29907853

SN - 0031-3998

VL - 84

SP - 159

EP - 164

JO - Pediatric Research

JF - Pediatric Research

IS - 2

ER -

Monitoring cerebral oxygenation of the immature brain: a neuroprotective strategy?

Abstract

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