Molecular typing methods for minor histocompatibility antigens.

Eric Spierings*, Els Goulmy

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)


Minor histocompatibility (H) antigens crucially affect the outcome of human leukocyte antigen-matched allogeneic stem cell transplantation. The number of molecularly identified minor H antigens is rapidly increasing. In parallel, clinical implementation of minor H antigens for immunotherapy has gained significant interest. It is therefore timely to type stem cell transplant recipients and their donors for minor H antigens. Here, we summarize all the currently known methodologies for minor H antigen typing on the genomic and on the RNA level.

Original languageEnglish
Pages (from-to)81-96
Number of pages16
JournalMethods in molecular medicine
Publication statusPublished - 2007


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