Molecular basis underlying resistance to Mps1/TTK inhibitors

Biochemistry, Genetics and Molecular Biology

• Cancer Cell 100%
• Cross Resistance 100%
• Wild Type 50%
• Enzymatic Activity 50%
• Phosphotransferase 50%
• Kinase 50%
• Adenosine Triphosphate 50%
• Cell Culture 50%
• Oncogene 50%
• Spindle Checkpoint 50%
• Enzyme Active Site 50%
• Drug Resistance 50%
• Point Mutation 50%
• Small Molecule 50%
• Dual-Specificity Kinase 50%