Molecular analysis of Tn1546-like elements in vancomycin-resistant enterococci isolated from patients in Europe shows geographic transposon type clustering

M A Schouten; R J Willems; W A Kraak; J Top; J A Hoogkamp-Korstanje; A Voss

doi:10.1128/AAC.45.3.986-989.2001

Molecular analysis of Tn1546-like elements in vancomycin-resistant enterococci isolated from patients in Europe shows geographic transposon type clustering

M A Schouten
, R J Willems
, W A Kraak
, J Top
, J A Hoogkamp-Korstanje
, A Voss

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Resistance mechanism relatedness was studied in 18 clinical, European vanA vancomycin-resistant enterococci. Molecular analysis revealed 10 Tn1546-like elements, suggesting two evolutionary lineages. Lineage I dominated the European mainland, and lineage II dominated the United Kingdom and Israel. Geographic clustering reflected different types of meat consumption between countries, since each lineage is associated with colonization of different animals.

Original language	English
Pages (from-to)	986-9
Number of pages	4
Journal	Antimicrobial Agents and Chemotherapy
Volume	45
Issue number	3
DOIs	https://doi.org/10.1128/AAC.45.3.986-989.2001
Publication status	Published - 2001

Keywords

Adolescent
Adult
Aged
Bacterial Proteins
Carbon-Oxygen Ligases
Child
Child, Preschool
DNA Transposable Elements
England
Enterococcus
Europe
Female
Humans
Infant
Male
Middle Aged
Vancomycin Resistance
Journal Article

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10.1128/AAC.45.3.986-989.2001

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@article{98ecd53082024c44963135288d1d7800,

title = "Molecular analysis of Tn1546-like elements in vancomycin-resistant enterococci isolated from patients in Europe shows geographic transposon type clustering",

abstract = "Resistance mechanism relatedness was studied in 18 clinical, European vanA vancomycin-resistant enterococci. Molecular analysis revealed 10 Tn1546-like elements, suggesting two evolutionary lineages. Lineage I dominated the European mainland, and lineage II dominated the United Kingdom and Israel. Geographic clustering reflected different types of meat consumption between countries, since each lineage is associated with colonization of different animals.",

keywords = "Adolescent, Adult, Aged, Bacterial Proteins, Carbon-Oxygen Ligases, Child, Child, Preschool, DNA Transposable Elements, England, Enterococcus, Europe, Female, Humans, Infant, Male, Middle Aged, Vancomycin Resistance, Journal Article",

author = "Schouten, \{M A\} and Willems, \{R J\} and Kraak, \{W A\} and J Top and Hoogkamp-Korstanje, \{J A\} and A Voss",

year = "2001",

doi = "10.1128/AAC.45.3.986-989.2001",

language = "English",

volume = "45",

pages = "986--9",

journal = "Antimicrobial Agents and Chemotherapy",

issn = "0066-4804",

publisher = "American Society for Microbiology",

number = "3",

}

TY - JOUR

T1 - Molecular analysis of Tn1546-like elements in vancomycin-resistant enterococci isolated from patients in Europe shows geographic transposon type clustering

AU - Schouten, M A

AU - Willems, R J

AU - Kraak, W A

AU - Top, J

AU - Hoogkamp-Korstanje, J A

AU - Voss, A

PY - 2001

Y1 - 2001

N2 - Resistance mechanism relatedness was studied in 18 clinical, European vanA vancomycin-resistant enterococci. Molecular analysis revealed 10 Tn1546-like elements, suggesting two evolutionary lineages. Lineage I dominated the European mainland, and lineage II dominated the United Kingdom and Israel. Geographic clustering reflected different types of meat consumption between countries, since each lineage is associated with colonization of different animals.

AB - Resistance mechanism relatedness was studied in 18 clinical, European vanA vancomycin-resistant enterococci. Molecular analysis revealed 10 Tn1546-like elements, suggesting two evolutionary lineages. Lineage I dominated the European mainland, and lineage II dominated the United Kingdom and Israel. Geographic clustering reflected different types of meat consumption between countries, since each lineage is associated with colonization of different animals.

KW - Adolescent

KW - Adult

KW - Aged

KW - Bacterial Proteins

KW - Carbon-Oxygen Ligases

KW - Child

KW - Child, Preschool

KW - DNA Transposable Elements

KW - England

KW - Enterococcus

KW - Europe

KW - Female

KW - Humans

KW - Infant

KW - Male

KW - Middle Aged

KW - Vancomycin Resistance

KW - Journal Article

U2 - 10.1128/AAC.45.3.986-989.2001

DO - 10.1128/AAC.45.3.986-989.2001

M3 - Article

C2 - 11181398

SN - 0066-4804

VL - 45

SP - 986

EP - 989

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

IS - 3

ER -

Molecular analysis of Tn1546-like elements in vancomycin-resistant enterococci isolated from patients in Europe shows geographic transposon type clustering

Abstract

Keywords

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