TY - JOUR
T1 - Microbiological testing of adults hospitalised with community-acquired pneumonia
T2 - An international study
AU - Carugati, Manuela
AU - Aliberti, Stefano
AU - Reyes, Luis Felipe
AU - Sadud, Ricardo Franco
AU - Irfan, Muhammad
AU - Prat, Cristina
AU - Soni, Nilam J.
AU - Faverio, Paola
AU - Gori, Andrea
AU - Blasi, Francesco
AU - Restrepo, Marcos I.
AU - Aruj, Patricia Karina
AU - Attorri, Silvia
AU - Barimboim, Enrique
AU - Caeiro, Juan Pablo
AU - Garzón, María I.
AU - Cambursano, Victor Hugo
AU - Ceccato, Adrian
AU - Chertcoff, Julio
AU - Díaz, Ariel Cordon
AU - De Vedia, Lautaro
AU - Ganaha, Maria Cristina
AU - Lambert, Sandra
AU - Lopardo, Gustavo
AU - Luna, Carlos M.
AU - Malberti, Alessio Gerardo
AU - Morcillo, Nora
AU - Tartara, Silvina
AU - Pensotti, Claudia
AU - Pereyra, Betiana
AU - Scapellato, Pablo Gustavo
AU - Stagnaro, Juan Pablo
AU - Shah, Sonali
AU - Lötsch, Felix
AU - Thalhammer, Florian
AU - Anseeuw, Kurt
AU - Francois, Camille A.
AU - Van Braeckel, Eva
AU - Vincent, Jean Louis
AU - Djimon, Marcel Zannou
AU - Bashi, Jules
AU - Dodo, Roger
AU - Nouér, Simone Aranha
AU - Chipev, Peter
AU - Encheva, Milena
AU - Miteva, Darina
AU - Petkova, Diana
AU - Balkissou, Adamou Dodo
AU - Yone, Eric Walter Pefura
AU - Ngahane, Bertrand Hugo Mbatchou
N1 - Publisher Copyright:
© ERS 2018.
PY - 2018/10/1
Y1 - 2018/10/1
N2 - This study aimed to describe real-life microbiological testing of adults hospitalised with community-acquired pneumonia (CAP) and to assess concordance with the 2007 Infectious Diseases Society of America (IDSA)/American Thoracic Society (ATS) and 2011 European Respiratory Society (ERS) CAP guidelines. This was a cohort study based on the Global Initiative for Methicillin-resistant Staphylococcus aureus Pneumonia (GLIMP) database, which contains point-prevalence data on adults hospitalised with CAP across 54 countries during 2015. In total, 3702 patients were included. Testing was performed in 3217 patients, and included blood culture (71.1%), sputum culture (61.8%), Legionella urinary antigen test (30.1%), pneumococcal urinary antigen test (30.0%), viral testing (14.9%), acute-phase serology (8.8%), bronchoalveolar lavage culture (8.4%) and pleural fluid culture (3.2%). A pathogen was detected in 1173 (36.5%) patients. Testing attitudes varied significantly according to geography and disease severity. Testing was concordant with IDSA/ATS and ERS guidelines in 16.7% and 23.9% of patients, respectively. IDSA/ATS concordance was higher in Europe than in North America (21.5% versus 9.8%; p<0.01), while ERS concordance was higher in North America than in Europe (33.5% versus 19.5%; p<0.01). Testing practices of adults hospitalised with CAP varied significantly by geography and disease severity. There was a wide discordance between real-life testing practices and IDSA/ATS/ERS guideline recommendations.
AB - This study aimed to describe real-life microbiological testing of adults hospitalised with community-acquired pneumonia (CAP) and to assess concordance with the 2007 Infectious Diseases Society of America (IDSA)/American Thoracic Society (ATS) and 2011 European Respiratory Society (ERS) CAP guidelines. This was a cohort study based on the Global Initiative for Methicillin-resistant Staphylococcus aureus Pneumonia (GLIMP) database, which contains point-prevalence data on adults hospitalised with CAP across 54 countries during 2015. In total, 3702 patients were included. Testing was performed in 3217 patients, and included blood culture (71.1%), sputum culture (61.8%), Legionella urinary antigen test (30.1%), pneumococcal urinary antigen test (30.0%), viral testing (14.9%), acute-phase serology (8.8%), bronchoalveolar lavage culture (8.4%) and pleural fluid culture (3.2%). A pathogen was detected in 1173 (36.5%) patients. Testing attitudes varied significantly according to geography and disease severity. Testing was concordant with IDSA/ATS and ERS guidelines in 16.7% and 23.9% of patients, respectively. IDSA/ATS concordance was higher in Europe than in North America (21.5% versus 9.8%; p<0.01), while ERS concordance was higher in North America than in Europe (33.5% versus 19.5%; p<0.01). Testing practices of adults hospitalised with CAP varied significantly by geography and disease severity. There was a wide discordance between real-life testing practices and IDSA/ATS/ERS guideline recommendations.
UR - https://www.scopus.com/pages/publications/85064437772
U2 - 10.1183/23120541.00096-2018
DO - 10.1183/23120541.00096-2018
M3 - Article
AN - SCOPUS:85064437772
SN - 2312-0541
VL - 4
JO - ERJ Open Research
JF - ERJ Open Research
IS - 4
M1 - 00096-2018
ER -