Methods and systems for predicting alloreactivity in transplantation

Ralf Schliehe-Diecks (Inventor), HT Spierings (Inventor)

Research output: PatentOther research output

Abstract

The invention relates to a method, system and/or data structure for carrying out a computer implemented method for determining the numbers of predicted indirectly recognized HLA epitopes (PIRCHES) between one or more donors and one or more recipients of transplantation material. The method, system and data structure described herein allow the identification of permissible mismatches and therefore relatively safe transplantation material by analysing via a computer implemented method HLA-derived peptides of patient and donor.
Original languageEnglish
Patent numberWO/2015/169597
Priority date22/04/15
Publication statusPublished - 12 Nov 2015

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