Abstract
Over the last years, interest in epigenetic mechanisms has strongly increased in the field of neuroscience. Neuroepigenetics has intensely evolved and now refers to the assessment of a variety of epigenetic marks which can be found across several regions of the healthy or diseased brain. These marks include DNA (hydroxy)methylation, a large diversity of post-translational histone modifications and an increasing number of non-coding RNAs. The present chapter aims to concisely summarize the techniques used to study these mechanisms in the brain and provides an overview of their current challenges along with future perspectives that will allow the field to move forward.
| Original language | English |
|---|---|
| Pages (from-to) | 15-27 |
| Number of pages | 13 |
| Journal | Progress in molecular biology and translational science |
| Volume | 158 |
| DOIs | |
| Publication status | Published - 1 Jan 2018 |
| Externally published | Yes |
Keywords
- DNA Methylation/genetics
- Epigenesis, Genetic
- Humans
- Nervous System/metabolism
- Organ Specificity/genetics
- Research Design
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