Metachromatic leukodystrophy: a 12-bp deletion in exon 2 of the arylsulfatase A gene in a late infantile variant

Jan A.F.M. Luyten*, Paul W. Wenink, Gerry C.H. Steenbergen-Spanjers, Ron A. Wevers, Hans Kristian Ploos van Amstel, Jan G.N. de Jong, Lambert P.W.J. van den Heuvel

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

13 Citations (Scopus)

Abstract

Sequencing of the arylsulfatase A gene in a late infantile metachromatic leukodystrophy patient showed the presence of a 12-bp deletion in exon 2. This deletion was found in a compound heterozygous state with the previously described 287 C→T transition.

Original languageEnglish
Pages (from-to)357-360
Number of pages4
JournalHuman Genetics
Volume96
Issue number3
DOIs
Publication statusPublished - 1 Sept 1995

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