TY - JOUR
T1 - Mental, cognitive and physical outcomes after intensive care unit treatment during the COVID-19 pandemic
T2 - a comparison between COVID-19 and non-COVID-19 patients
AU - van Houwelingen, Fedor
AU - van Dellen, Edwin
AU - Visser-Meily, J. M.Anne
AU - Valkenet, Karin
AU - Heijnen, Germijn H.
AU - Vernooij, Lisette M.
AU - Kerckhoffs, Monika C.
AU - Slooter, Arjen J.C.
N1 - Funding Information:
We would like to thank Bas Cijs for his contribution to the study plan and collecting data. We thank Jacqueline Vromen and Willem Broeders for their assistance with retrieving the data.
Publisher Copyright:
© 2023, Springer Nature Limited.
Publisher Copyright:
© 2023, Springer Nature Limited.
PY - 2023/9/2
Y1 - 2023/9/2
N2 - To compare mental, cognitive and physical outcomes between COVID-19 and non-COVID-19 patients, 3–6 months after Intensive Care Unit (ICU) treatment during the COVID-19 pandemic and to compare mental outcomes between relatives of these patients. This retrospective cohort study included 209 ICU survivors (141 COVID-19 patients and 68 non-COVID-19 patients) and 168 of their relatives (maximum one per patient) during the COVID-19 pandemic. Primary outcomes were self-reported occurrence of mental, cognitive and/or physical symptoms 3–6 months after ICU discharge. The occurrence of mental symptoms did not differ between former COVID-19 patients (34.7% [43/124]) and non-COVID-19 patients (43.5% [27/62]) (p = 0.309), neither between relatives of COVID-19 patients (37.6% [38/101]) and relatives of non-COVID-19 patients (39.6% [21/53]) (p = 0.946). Depression scores on the Hospital Anxiety and Depression Scale were lower in former COVID-19 patients, compared to non-COVID-19 patients (p = 0.025). We found no differences between COVID-19 and non-COVID-19 patients in cognitive and physical outcomes. Mental, cognitive and physical outcomes in COVID-19 ICU survivors were similar to non-COVID-19 ICU survivors. Mental symptoms in relatives of COVID-19 ICU survivors did not differ from relatives of non-COVID-19 ICU survivors, within the same time frame.
AB - To compare mental, cognitive and physical outcomes between COVID-19 and non-COVID-19 patients, 3–6 months after Intensive Care Unit (ICU) treatment during the COVID-19 pandemic and to compare mental outcomes between relatives of these patients. This retrospective cohort study included 209 ICU survivors (141 COVID-19 patients and 68 non-COVID-19 patients) and 168 of their relatives (maximum one per patient) during the COVID-19 pandemic. Primary outcomes were self-reported occurrence of mental, cognitive and/or physical symptoms 3–6 months after ICU discharge. The occurrence of mental symptoms did not differ between former COVID-19 patients (34.7% [43/124]) and non-COVID-19 patients (43.5% [27/62]) (p = 0.309), neither between relatives of COVID-19 patients (37.6% [38/101]) and relatives of non-COVID-19 patients (39.6% [21/53]) (p = 0.946). Depression scores on the Hospital Anxiety and Depression Scale were lower in former COVID-19 patients, compared to non-COVID-19 patients (p = 0.025). We found no differences between COVID-19 and non-COVID-19 patients in cognitive and physical outcomes. Mental, cognitive and physical outcomes in COVID-19 ICU survivors were similar to non-COVID-19 ICU survivors. Mental symptoms in relatives of COVID-19 ICU survivors did not differ from relatives of non-COVID-19 ICU survivors, within the same time frame.
KW - COVID-19/epidemiology
KW - Cognition
KW - Humans
KW - Intensive Care Units
KW - Pandemics
KW - Retrospective Studies
UR - http://www.scopus.com/inward/record.url?scp=85169523722&partnerID=8YFLogxK
U2 - 10.1038/s41598-023-41667-4
DO - 10.1038/s41598-023-41667-4
M3 - Article
C2 - 37660228
SN - 2045-2322
VL - 13
JO - Scientific Reports
JF - Scientific Reports
IS - 1
M1 - 14414
ER -