Abstract
By beautiful imaging and state-of-the-art experiments, vinculin is established to be a central switch in mechanotransduction at integrin-based focal adhesions. Cycles of tension-regulated vinculin switching control focal adhesion dynamics and signaling to enable polarized cell migration and alignment.
| Translated title of the contribution | Mechanotransduction: vinculin provides stability when tension rises. |
|---|---|
| Original language | Undefined/Unknown |
| Pages (from-to) | R159-61 |
| Number of pages | 3 |
| Journal | Current Biology |
| Volume | 23 |
| Issue number | 4 |
| Publication status | Published - 2013 |