MATIG RESULTAAT VAN BEHANDELING VAN ECHINOKOKKOSE MET ALBENDAZOL BIJ 7 PATIENTEN

Translated title of the contribution: Poor results of albendazole treatment of echinococcosis in 7 patients

P. M. Schneeberger, L. M. Kortbeek, M. M E Schneider, S. P M Geelen, M. S. Van Leeuwen, I. M. Hoepelman*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Abstract

Objective. To assess the effect of treatment of echinococcal disease with albendazole, a drug recently licensed in the Netherlands for this treatment. Setting. The University Hospital Utrecht and the Wilhelmina Children's Hospital, Utrecht. Design. Follow-up study. Method. Clinical symptoms, serology and size and morphology of cysts of all patients (n = 7) treated with albendazole with a therapeutical dose (10 mg/kg for adults and 6 mg/kg for children in two daily doses during three cycles of 28 days) were monitored for at least one year. Results. Two patients improved, two patients did not show any change, and the condition of three patients deteriorated. Conclusion. The efficacy of albendazole treatment with this regimen for hydatid disease is disappointing. If patients are treated with albendazole, the total dose administered to adults should be more than 80 g.

Translated title of the contributionPoor results of albendazole treatment of echinococcosis in 7 patients
Original languageDutch
Pages (from-to)460-463
Number of pages4
JournalNederlands Tijdschrift voor Geneeskunde
Volume138
Issue number9
Publication statusPublished - 1994

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