Malaria in pregnancy: the difficulties in measuring birthweight

M.J. Rijken, J.A. Rijken, A.T. Papageorghiou, S.H Kennedy, G.H.A. Visser, F. Nosten, R. McGready

Research output: Contribution to journalReview articlepeer-review

Abstract

Recommendations for interventions to control malaria in pregnancy are often based on studies using birthweight as the primary endpoint. Differences in birthweight may be attributable partly to methodological difficulties. We performed a structured search of the literature using 'malaria', 'pregnancy' and 'birth weight' as search terms. Of the clinical trials reporting birthweight, only 33% (14/43) gave information about the timing of the measurement and details on the scales used. Seventy seven per cent explained how gestational age was estimated. We propose a standardised method for the measurement and reporting of birthweight in future studies.

Original languageEnglish
Pages (from-to)671-678
Number of pages8
JournalBJOG - An International Journal of Obstetrics and Gynaecology
Volume118
Issue number6
DOIs
Publication statusPublished - 2011

Keywords

  • Birth Weight
  • Confounding Factors (Epidemiology)
  • Female
  • Gestational Age
  • Humans
  • Infant, Newborn
  • Malaria
  • Pregnancy
  • Pregnancy Complications, Parasitic
  • Pregnancy Outcome
  • Reference Standards
  • Ultrasonography, Prenatal
  • Journal Article
  • Research Support, Non-U.S. Gov't
  • Review

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