TY - JOUR
T1 - Lymphokines induce changes in morphology and enhance motility of endothelial cells
AU - Groenewegen, Gerard
AU - Buurman, Wim A.
AU - van der Linden, Cees J.
PY - 1985/1/1
Y1 - 1985/1/1
N2 - The influence of lymphokines, the soluble mediators produced by lymphocytes, on the morphology and the motility of endothelial cells in vitro is described. Lymphokines induced an altered morphology and an increased motility of canine and human venous endothelial cells. The action of the lymphokines was species specific. The data are discussed in relation to in vitro and in vivo data on the behavior of endothelial cells in inflammation. The in vitro experiments allow further study of the role of endothelial cells in inflammatory and immunological processes.
AB - The influence of lymphokines, the soluble mediators produced by lymphocytes, on the morphology and the motility of endothelial cells in vitro is described. Lymphokines induced an altered morphology and an increased motility of canine and human venous endothelial cells. The action of the lymphokines was species specific. The data are discussed in relation to in vitro and in vivo data on the behavior of endothelial cells in inflammation. The in vitro experiments allow further study of the role of endothelial cells in inflammatory and immunological processes.
UR - http://www.scopus.com/inward/record.url?scp=0022006975&partnerID=8YFLogxK
U2 - 10.1016/0090-1229(85)90058-3
DO - 10.1016/0090-1229(85)90058-3
M3 - Article
C2 - 4017294
AN - SCOPUS:0022006975
SN - 0090-1229
VL - 36
SP - 378
EP - 385
JO - Clinical Immunology and Immunopathology
JF - Clinical Immunology and Immunopathology
IS - 3
ER -