Lung cancer risk among bakers, pastrycooks and confectionary makers: The SYNERGY study

Thomas Behrens; Benjamin Kendzia; Tabea Treppmann; Ann C. Olsson; Karl Heinz Jöckel; Per Gustavsson; Hermann Pohlabeln; Wolfgang Ahrens; Irene Brüske; Hans Erich Wichmann; Franco Merletti; Dario Mirabelli; Lorenzo Richiardi; Lorenzo Simonato; David Zaridze; Neonila Szeszenia-Dabrowska; Peter Rudnai; Jolanta Lissowska; Eleonora Fabianova; Adonina Tardón; John K. Field; Rodica Stanescu Dumitru; Vladimir Bencko; Lenka Foretova; Vladimir Janout; Jack Siemiatycki; Marie Elise Parent; John McLaughlin; Paul Demers; Maria Teresa Landi; Neil E Caporaso; Hans Kromhout; Roel Vermeulen; Susan Peters; Simone Benhamou; Isabelle Stücker; Florence Guida; Dario Consonni; Bas Bueno-de-Mesquita; Andrea‘ T. Mannetje; Neil Pearce; Lap Ah Tse; Ignatius Tak Sun Yu; Nils Plato; Paolo Boffetta; Kurt Straif; Joachim Schüz; Beate Pesch; Thomas Brüning

doi:10.1136/oemed-2013-101469

Lung cancer risk among bakers, pastrycooks and confectionary makers: The SYNERGY study

Thomas Behrens^*, Benjamin Kendzia, Tabea Treppmann, Ann C. Olsson, Karl Heinz Jöckel, Per Gustavsson, Hermann Pohlabeln, Wolfgang Ahrens, Irene Brüske, Hans Erich Wichmann, Franco Merletti, Dario Mirabelli, Lorenzo Richiardi, Lorenzo Simonato, David Zaridze, Neonila Szeszenia-Dabrowska, Peter Rudnai, Jolanta Lissowska, Eleonora Fabianova, Adonina TardónJohn K. Field, Rodica Stanescu Dumitru, Vladimir Bencko, Lenka Foretova, Vladimir Janout, Jack Siemiatycki, Marie Elise Parent, John McLaughlin, Paul Demers, Maria Teresa Landi, Neil E Caporaso, Hans Kromhout, Roel Vermeulen, Susan Peters, Simone Benhamou, Isabelle Stücker, Florence Guida, Dario Consonni, Bas Bueno-de-Mesquita, Andrea‘ T. Mannetje, Neil Pearce, Lap Ah Tse, Ignatius Tak Sun Yu, Nils Plato, Paolo Boffetta, Kurt Straif, Joachim Schüz, Beate Pesch, Thomas Brüning

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

4 Citations (Scopus)

Abstract

Introduction: Some studies have suggested increased lung cancer risks among bakers, however the results overall were inconsistent. The authors studied lung cancer risks among bakers and baking-related occupations in the SYNERGY pooled case-control database from 16 countries. Methods: Occupation in a baking-related job was identi fied from the subjects' job histories. ORs adjusted for log(age), study centre, smoking behaviour and ever employment in a job with known exposure to occupational lung carcinogens were calculated by unconditional logistic regression. Findings were stratified by sex, histological subtype of lung cancer and smoking status. Results: 19 366 cases (15 606 men) and 23 670 control subjects (18 528 men) were included. 473 cases (415 men, 58 women) and 501 controls (437 men, 64 women) had ever worked in baking or a related job. We did not observe an increased risk for men in baking (OR 1.01; 95% CI 0.86 to 1.18). No linear trends were observed for duration of employment. Some results suggested increased lung cancer risks for women, for example, for working as a baker for >30 years and in never-smokers, but after exclusion of one study these increased risks disappeared. Discussion: The findings from this study do not suggest increased lung cancer risks in baking-related professions.

Original language	English
Pages (from-to)	810-814
Number of pages	5
Journal	Occupational and Environmental Medicine
Volume	70
Issue number	11
DOIs	https://doi.org/10.1136/oemed-2013-101469
Publication status	Published - Nov 2013
Externally published	Yes

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Behrens, T., Kendzia, B., Treppmann, T., Olsson, A. C., Jöckel, K. H., Gustavsson, P., Pohlabeln, H., Ahrens, W., Brüske, I., Wichmann, H. E., Merletti, F., Mirabelli, D., Richiardi, L., Simonato, L., Zaridze, D., Szeszenia-Dabrowska, N., Rudnai, P., Lissowska, J., Fabianova, E., ... Brüning, T. (2013). Lung cancer risk among bakers, pastrycooks and confectionary makers: The SYNERGY study. Occupational and Environmental Medicine, 70(11), 810-814. https://doi.org/10.1136/oemed-2013-101469

@article{4bd85fa55c6e4482a469eb489084e44d,

title = "Lung cancer risk among bakers, pastrycooks and confectionary makers: The SYNERGY study",

abstract = "Introduction: Some studies have suggested increased lung cancer risks among bakers, however the results overall were inconsistent. The authors studied lung cancer risks among bakers and baking-related occupations in the SYNERGY pooled case-control database from 16 countries. Methods: Occupation in a baking-related job was identi fied from the subjects' job histories. ORs adjusted for log(age), study centre, smoking behaviour and ever employment in a job with known exposure to occupational lung carcinogens were calculated by unconditional logistic regression. Findings were stratified by sex, histological subtype of lung cancer and smoking status. Results: 19 366 cases (15 606 men) and 23 670 control subjects (18 528 men) were included. 473 cases (415 men, 58 women) and 501 controls (437 men, 64 women) had ever worked in baking or a related job. We did not observe an increased risk for men in baking (OR 1.01; 95% CI 0.86 to 1.18). No linear trends were observed for duration of employment. Some results suggested increased lung cancer risks for women, for example, for working as a baker for >30 years and in never-smokers, but after exclusion of one study these increased risks disappeared. Discussion: The findings from this study do not suggest increased lung cancer risks in baking-related professions.",

author = "Thomas Behrens and Benjamin Kendzia and Tabea Treppmann and Olsson, {Ann C.} and J{\"o}ckel, {Karl Heinz} and Per Gustavsson and Hermann Pohlabeln and Wolfgang Ahrens and Irene Br{\"u}ske and Wichmann, {Hans Erich} and Franco Merletti and Dario Mirabelli and Lorenzo Richiardi and Lorenzo Simonato and David Zaridze and Neonila Szeszenia-Dabrowska and Peter Rudnai and Jolanta Lissowska and Eleonora Fabianova and Adonina Tard{\'o}n and Field, {John K.} and Dumitru, {Rodica Stanescu} and Vladimir Bencko and Lenka Foretova and Vladimir Janout and Jack Siemiatycki and Parent, {Marie Elise} and John McLaughlin and Paul Demers and Landi, {Maria Teresa} and Caporaso, {Neil E} and Hans Kromhout and Roel Vermeulen and Susan Peters and Simone Benhamou and Isabelle St{\"u}cker and Florence Guida and Dario Consonni and Bas Bueno-de-Mesquita and Mannetje, {Andrea{\textquoteleft} T.} and Neil Pearce and Tse, {Lap Ah} and Yu, {Ignatius Tak Sun} and Nils Plato and Paolo Boffetta and Kurt Straif and Joachim Sch{\"u}z and Beate Pesch and Thomas Br{\"u}ning",

year = "2013",

month = nov,

doi = "10.1136/oemed-2013-101469",

language = "English",

volume = "70",

pages = "810--814",

journal = "Occupational and Environmental Medicine",

issn = "1351-0711",

publisher = "BMJ Publishing Group",

number = "11",

}

Behrens, T, Kendzia, B, Treppmann, T, Olsson, AC, Jöckel, KH, Gustavsson, P, Pohlabeln, H, Ahrens, W, Brüske, I, Wichmann, HE, Merletti, F, Mirabelli, D, Richiardi, L, Simonato, L, Zaridze, D, Szeszenia-Dabrowska, N, Rudnai, P, Lissowska, J, Fabianova, E, Tardón, A, Field, JK, Dumitru, RS, Bencko, V, Foretova, L, Janout, V, Siemiatycki, J, Parent, ME, McLaughlin, J, Demers, P, Landi, MT, Caporaso, NE, Kromhout, H, Vermeulen, R, Peters, S, Benhamou, S, Stücker, I, Guida, F, Consonni, D, Bueno-de-Mesquita, B, Mannetje, AT, Pearce, N, Tse, LA, Yu, ITS, Plato, N, Boffetta, P, Straif, K, Schüz, J, Pesch, B & Brüning, T 2013, 'Lung cancer risk among bakers, pastrycooks and confectionary makers: The SYNERGY study', Occupational and Environmental Medicine, vol. 70, no. 11, pp. 810-814. https://doi.org/10.1136/oemed-2013-101469

TY - JOUR

T1 - Lung cancer risk among bakers, pastrycooks and confectionary makers

T2 - The SYNERGY study

AU - Behrens, Thomas

AU - Kendzia, Benjamin

AU - Treppmann, Tabea

AU - Olsson, Ann C.

AU - Jöckel, Karl Heinz

AU - Gustavsson, Per

AU - Pohlabeln, Hermann

AU - Ahrens, Wolfgang

AU - Brüske, Irene

AU - Wichmann, Hans Erich

AU - Merletti, Franco

AU - Mirabelli, Dario

AU - Richiardi, Lorenzo

AU - Simonato, Lorenzo

AU - Zaridze, David

AU - Szeszenia-Dabrowska, Neonila

AU - Rudnai, Peter

AU - Lissowska, Jolanta

AU - Fabianova, Eleonora

AU - Tardón, Adonina

AU - Field, John K.

AU - Dumitru, Rodica Stanescu

AU - Bencko, Vladimir

AU - Foretova, Lenka

AU - Janout, Vladimir

AU - Siemiatycki, Jack

AU - Parent, Marie Elise

AU - McLaughlin, John

AU - Demers, Paul

AU - Landi, Maria Teresa

AU - Caporaso, Neil E

AU - Kromhout, Hans

AU - Vermeulen, Roel

AU - Peters, Susan

AU - Benhamou, Simone

AU - Stücker, Isabelle

AU - Guida, Florence

AU - Consonni, Dario

AU - Bueno-de-Mesquita, Bas

AU - Mannetje, Andrea‘ T.

AU - Pearce, Neil

AU - Tse, Lap Ah

AU - Yu, Ignatius Tak Sun

AU - Plato, Nils

AU - Boffetta, Paolo

AU - Straif, Kurt

AU - Schüz, Joachim

AU - Pesch, Beate

AU - Brüning, Thomas

PY - 2013/11

Y1 - 2013/11

N2 - Introduction: Some studies have suggested increased lung cancer risks among bakers, however the results overall were inconsistent. The authors studied lung cancer risks among bakers and baking-related occupations in the SYNERGY pooled case-control database from 16 countries. Methods: Occupation in a baking-related job was identi fied from the subjects' job histories. ORs adjusted for log(age), study centre, smoking behaviour and ever employment in a job with known exposure to occupational lung carcinogens were calculated by unconditional logistic regression. Findings were stratified by sex, histological subtype of lung cancer and smoking status. Results: 19 366 cases (15 606 men) and 23 670 control subjects (18 528 men) were included. 473 cases (415 men, 58 women) and 501 controls (437 men, 64 women) had ever worked in baking or a related job. We did not observe an increased risk for men in baking (OR 1.01; 95% CI 0.86 to 1.18). No linear trends were observed for duration of employment. Some results suggested increased lung cancer risks for women, for example, for working as a baker for >30 years and in never-smokers, but after exclusion of one study these increased risks disappeared. Discussion: The findings from this study do not suggest increased lung cancer risks in baking-related professions.

AB - Introduction: Some studies have suggested increased lung cancer risks among bakers, however the results overall were inconsistent. The authors studied lung cancer risks among bakers and baking-related occupations in the SYNERGY pooled case-control database from 16 countries. Methods: Occupation in a baking-related job was identi fied from the subjects' job histories. ORs adjusted for log(age), study centre, smoking behaviour and ever employment in a job with known exposure to occupational lung carcinogens were calculated by unconditional logistic regression. Findings were stratified by sex, histological subtype of lung cancer and smoking status. Results: 19 366 cases (15 606 men) and 23 670 control subjects (18 528 men) were included. 473 cases (415 men, 58 women) and 501 controls (437 men, 64 women) had ever worked in baking or a related job. We did not observe an increased risk for men in baking (OR 1.01; 95% CI 0.86 to 1.18). No linear trends were observed for duration of employment. Some results suggested increased lung cancer risks for women, for example, for working as a baker for >30 years and in never-smokers, but after exclusion of one study these increased risks disappeared. Discussion: The findings from this study do not suggest increased lung cancer risks in baking-related professions.

UR - http://www.scopus.com/inward/record.url?scp=84885871503&partnerID=8YFLogxK

U2 - 10.1136/oemed-2013-101469

DO - 10.1136/oemed-2013-101469

M3 - Article

C2 - 23911873

AN - SCOPUS:84885871503

SN - 1351-0711

VL - 70

SP - 810

EP - 814

JO - Occupational and Environmental Medicine

JF - Occupational and Environmental Medicine

IS - 11

ER -

Lung cancer risk among bakers, pastrycooks and confectionary makers: The SYNERGY study

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