TY - JOUR
T1 - Longitudinal Motor-Developmental Outcomes in Infants with a Critical Congenital Heart Defect
AU - Sprong, Maaike C A
AU - van Brussel, Marco
AU - de Vries, Linda S
AU - van der Net, Janjaap
AU - Nijman, Joppe
AU - Breur, Johannes M P J
AU - Slieker, Martijn G
N1 - Funding Information:
Acknowledgments: The authors would like to thank the patients and their parents who participated in the study. The study was made possible through financial support from the Hartekind foundation and the K.F.Hein Foundation. The funding sources had no involvement in the conduct of the research or preparation of the article.
Publisher Copyright:
© 2022 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2022/4/16
Y1 - 2022/4/16
N2 - Infants with critical congenital heart defects (CCHDs) are at increased risk for neurodevelopmental delays. The early identification of motor delays is clinically relevant to prevent or reduce long-term consequences. The current study aims to describe the motor-developmental pathways of infants with a CCHD. Motor development was assessed in 215 infants and toddlers using the Dutch version of the Bayley-III. At 3 months (n = 165), 9 months (n = 188), and 18 months (n = 171) the motor composite scores were 97, 98, and 104, respectively. A motor composite score of ≤-2 SD was only seen in 2.4%, 0%, and 2.3%, respectively, with gross motor deficits being observed more often than fine motor deficits (12% vs. 0% at 18 months). Over 90% of infants who scored average at 9 months still did so at 18 months. The majority of infants with below-average gross motor scores (≤-1) at 9 months still had a below-average or delayed motor score (≤-2 SD) at 18 months. Abnormal gross motor scores (≤-2 SD) increased with age. Infants with single-ventricle physiology performed significantly (p ≤ 0.05) worse on both fine and gross motor skills at 9 and 18 months compared to infants with other CCHDs.
AB - Infants with critical congenital heart defects (CCHDs) are at increased risk for neurodevelopmental delays. The early identification of motor delays is clinically relevant to prevent or reduce long-term consequences. The current study aims to describe the motor-developmental pathways of infants with a CCHD. Motor development was assessed in 215 infants and toddlers using the Dutch version of the Bayley-III. At 3 months (n = 165), 9 months (n = 188), and 18 months (n = 171) the motor composite scores were 97, 98, and 104, respectively. A motor composite score of ≤-2 SD was only seen in 2.4%, 0%, and 2.3%, respectively, with gross motor deficits being observed more often than fine motor deficits (12% vs. 0% at 18 months). Over 90% of infants who scored average at 9 months still did so at 18 months. The majority of infants with below-average gross motor scores (≤-1) at 9 months still had a below-average or delayed motor score (≤-2 SD) at 18 months. Abnormal gross motor scores (≤-2 SD) increased with age. Infants with single-ventricle physiology performed significantly (p ≤ 0.05) worse on both fine and gross motor skills at 9 and 18 months compared to infants with other CCHDs.
KW - Bayley-III
KW - cardiac surgery
KW - children
KW - critical congenital heart disease
KW - gross motor delay
KW - infants
KW - motor development
KW - neurodevelopmental outcomes
UR - http://www.scopus.com/inward/record.url?scp=85129192027&partnerID=8YFLogxK
U2 - 10.3390/children9040570
DO - 10.3390/children9040570
M3 - Article
C2 - 35455614
SN - 2227-9067
VL - 9
SP - 1
EP - 16
JO - Children (Basel, Switzerland)
JF - Children (Basel, Switzerland)
IS - 4
M1 - 570
ER -