Long-term trajectories of health-related quality of life in individuals with cerebral palsy: a multicenter longitudinal study

Siok Swan Tan, Jetty van Meeteren, Marjolijn Ketelaar, Carlo Schuengel, Heleen A Reinders-Messelink, Hein Raat, Annet J Dallmeijer, Marij E Roebroeck,

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

OBJECTIVES: To (1) determine the long-term trajectory of health-related quality of life (HRQOL) for the dimensions of physical complaints and motor, psychological, and social functioning for groups of individuals with cerebral palsy (CP) aged 1 to 24 years; (2) assess the variability in HRQOL within individuals with CP over time; (3) assess the variability in HRQOL between individuals with CP; and (4) compare the HRQOL in individuals with CP to reference data of typically developing individuals.

DESIGN: Multicenter prospective longitudinal study.

SETTING: Rehabilitation departments of 3 university medical centers and various rehabilitation centers in The Netherlands.

PARTICIPANTS: Dutch individuals with CP (N=424; age, 1-24y).

INTERVENTIONS: Not applicable.

MAIN OUTCOME MEASURES: The HRQOL dimensions of physical complaints and motor, psychological, and social functioning. Each individual visited the rehabilitation department for 3 or 4 measurements. The time between measurements was 1 or 2 years.

RESULTS: Individuals with CP experience an HRQOL that, on average, remains fairly stable over time. Variability in HRQOL within individuals with CP was similar to that within typically developing individuals. Variability between individuals with CP could be explained by type of CP (motor functioning), Gross Motor Function Classification System level (physical complaints and motor and social functioning), and intellectual disability (physical complaints and social functioning). Finally, individuals with CP experienced a lower HRQOL than did typically developing individuals, especially for the dimensions of motor and social functioning.

CONCLUSIONS: Many changes take place in the psychosocial development of the individual with CP, which accordingly change their expectations and those of their caregivers, peers, and professionals. As a result, perceived physical complaints and motor, psychological, and social functioning remain fairly stable over many years.

Original languageEnglish
Pages (from-to)2029-2039
Number of pages11
JournalArchives of Physical Medicine and Rehabilitation
Volume95
Issue number11
DOIs
Publication statusPublished - Nov 2014

Keywords

  • Adolescent
  • Cerebral Palsy
  • Child, Preschool
  • Female
  • Health Status
  • Humans
  • Infant
  • Intellectual Disability
  • Longitudinal Studies
  • Male
  • Psychomotor Performance
  • Quality of Life
  • Severity of Illness Index
  • Social Participation
  • Time Factors
  • Young Adult

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