TY - JOUR
T1 - Long-term outcome after surgery for pulmonary stenosis (a longitudinal study of 22-33 years)
AU - Roos-Hesselink, J. W.
AU - Meijboom, F. J.
AU - Spitaels, S. E.C.
AU - VanDomburg, R. T.
AU - VanRijen, E. H.M.
AU - Utens, E. M.W.J.
AU - Bogers, A. J.J.C.
AU - Simoons, M. L.
PY - 2006/2/1
Y1 - 2006/2/1
N2 - Aims: Long-term (>20 years) survival and clinical outcome are only partly documented in patients who underwent surgical repair for isolated pulmonary stenosis. Yet, such data are of critical importance for the future perspectives, medical care, employability, and insurability of these patients. Methods and results: Ninety consecutive patients underwent surgery for pulmonary stenosis between 1968 and 1980 at the Thoraxcenter. A systematic follow-up study was performed in 1990 and again in 2001. Survival after 25 years was 93%. Re-intervention was necessary in 15% of the patients, mainly for pulmonary regurgitation. Right atrial and ventricular dilatation and paradoxical septal motion were associated with the need for reoperation. No major ventricular arrhythmias occurred. Supraventricular arrhythmias occurred, only in patients with severe pulmonary regurgitation and disappeared after reoperation. At last follow-up, 67% of the patients was in NYHA Class I and maximal exercise capacity was 90% of normal. Moderate or severe pulmonary regurgitation was present in 37% of the patients. Conclusion: Although long-term survival and quality of life are good, pulmonary regurgitation is found in a third of the patients 22-33 years after surgical repair for isolated pulmonary stenosis and reoperation for pulmonary regurgitation was necessary in 9%, especially after the transannular patch technique.
AB - Aims: Long-term (>20 years) survival and clinical outcome are only partly documented in patients who underwent surgical repair for isolated pulmonary stenosis. Yet, such data are of critical importance for the future perspectives, medical care, employability, and insurability of these patients. Methods and results: Ninety consecutive patients underwent surgery for pulmonary stenosis between 1968 and 1980 at the Thoraxcenter. A systematic follow-up study was performed in 1990 and again in 2001. Survival after 25 years was 93%. Re-intervention was necessary in 15% of the patients, mainly for pulmonary regurgitation. Right atrial and ventricular dilatation and paradoxical septal motion were associated with the need for reoperation. No major ventricular arrhythmias occurred. Supraventricular arrhythmias occurred, only in patients with severe pulmonary regurgitation and disappeared after reoperation. At last follow-up, 67% of the patients was in NYHA Class I and maximal exercise capacity was 90% of normal. Moderate or severe pulmonary regurgitation was present in 37% of the patients. Conclusion: Although long-term survival and quality of life are good, pulmonary regurgitation is found in a third of the patients 22-33 years after surgical repair for isolated pulmonary stenosis and reoperation for pulmonary regurgitation was necessary in 9%, especially after the transannular patch technique.
KW - Congenital heart defect
KW - Follow-up study
KW - Pulmonary stenosis
KW - Survival
UR - http://www.scopus.com/inward/record.url?scp=32144438479&partnerID=8YFLogxK
U2 - 10.1093/eurheartj/ehi685
DO - 10.1093/eurheartj/ehi685
M3 - Article
C2 - 16361324
AN - SCOPUS:32144438479
SN - 0195-668X
VL - 27
SP - 482
EP - 488
JO - European heart journal
JF - European heart journal
IS - 4
ER -