TY - JOUR
T1 - Long-term Changes in Personal Recovery and Quality of Life Among Patients With Schizophrenia Spectrum Disorders and Different Durations of Illness
T2 - A Meta-analysis
AU - de Winter, Lars
AU - Jelsma, Auke
AU - Vermeulen, Jentien M
AU - van Weeghel, Jaap
AU - Hasson-Ohayon, Ilanit
AU - Mulder, Cornelis L
AU - Boonstra, Nynke
AU - Veling, Wim
AU - de Haan, Lieuwe
N1 - Publisher Copyright:
© The Author(s) 2024. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center.
PY - 2024/12/20
Y1 - 2024/12/20
N2 - BACKGROUND AND HYPOTHESIS: In schizophrenia spectrum disorders (SSD) personal recovery and subjective quality of life (S-QOL) are crucial and show conceptual overlap. There is limited knowledge about how these outcomes change over time. Therefore, we investigated changes in personal recovery or S-QOL for patients with SSD. We specifically focused on the influence of the patients' durations of illness (DOI) on changes in personal recovery and S-QOL.STUDY DESIGN: We included 46 studies investigating longitudinal changes in quantitative assessments of personal recovery or S-QOL for patients with SSD. Outcomes were categorized in overall personal recovery, overall S-QOL connectedness, hope and optimism, identity, meaning in life, and empowerment. We evaluated effect sizes of change between baseline and follow-up assessments. We also evaluated potential moderating effects, including DOI on these changes in outcomes.STUDY RESULTS: We found small improvements of overall personal recovery and S-QOL, but marginal or no improvement over time in the other more specific outcome domains. Patients without a schizophrenia diagnosis, a younger age, and more recent publications positively influenced these changes. We found no significant influence of DOI on the changes in any outcome domain.CONCLUSIONS: Improvement in personal recovery or S-QOL of people with SSD is modest at best. However, these studies did not fully capture the personal narratives or nonlinear process of recovery of an individual. Future research should focus on how to shift from a clinical to more person-oriented approach in clinical practice to support patients in improving their personal process of recovery.REVIEW PROTOCOL REGISTRATION: CRD42022377100.
AB - BACKGROUND AND HYPOTHESIS: In schizophrenia spectrum disorders (SSD) personal recovery and subjective quality of life (S-QOL) are crucial and show conceptual overlap. There is limited knowledge about how these outcomes change over time. Therefore, we investigated changes in personal recovery or S-QOL for patients with SSD. We specifically focused on the influence of the patients' durations of illness (DOI) on changes in personal recovery and S-QOL.STUDY DESIGN: We included 46 studies investigating longitudinal changes in quantitative assessments of personal recovery or S-QOL for patients with SSD. Outcomes were categorized in overall personal recovery, overall S-QOL connectedness, hope and optimism, identity, meaning in life, and empowerment. We evaluated effect sizes of change between baseline and follow-up assessments. We also evaluated potential moderating effects, including DOI on these changes in outcomes.STUDY RESULTS: We found small improvements of overall personal recovery and S-QOL, but marginal or no improvement over time in the other more specific outcome domains. Patients without a schizophrenia diagnosis, a younger age, and more recent publications positively influenced these changes. We found no significant influence of DOI on the changes in any outcome domain.CONCLUSIONS: Improvement in personal recovery or S-QOL of people with SSD is modest at best. However, these studies did not fully capture the personal narratives or nonlinear process of recovery of an individual. Future research should focus on how to shift from a clinical to more person-oriented approach in clinical practice to support patients in improving their personal process of recovery.REVIEW PROTOCOL REGISTRATION: CRD42022377100.
KW - changes
KW - course
KW - meta-analysis
KW - personal recovery
KW - psychosis
KW - schizophrenia spectrum disorders
KW - subjective quality of life
UR - http://www.scopus.com/inward/record.url?scp=85203028551&partnerID=8YFLogxK
U2 - 10.1093/schbul/sbae045
DO - 10.1093/schbul/sbae045
M3 - Article
C2 - 38613256
SN - 0586-7614
VL - 51
SP - 37
EP - 53
JO - Schizophrenia bulletin
JF - Schizophrenia bulletin
IS - 1
ER -