TY - JOUR
T1 - Long sleep duration is associated with lower cognitive function among middle-age adults – the Doetinchem Cohort Study
AU - van Oostrom, Sandra H.
AU - Nooyens, Astrid C.J.
AU - van Boxtel, Martin P.J.
AU - Verschuren, W. M.Monique
N1 - Funding Information:
The Doetinchem Cohort Study is funded by the National Institute for Public Health and the Environment , which works under the authority of the Ministry of Health, Welfare and Sport of the Netherlands . The authors would like to thank the epidemiologists and fieldworkers of the Municipal Health Service in Doetinchem for their contribution to the data collection for this study.
Funding Information:
The Doetinchem Cohort Study is funded by the National Institute for Public Health and the Environment, which works under the authority of the Ministry of Health, Welfare and Sport of the Netherlands. The authors would like to thank the epidemiologists and fieldworkers of the Municipal Health Service in Doetinchem for their contribution to the data collection for this study.
Publisher Copyright:
© 2017 The Authors
PY - 2018/1/1
Y1 - 2018/1/1
N2 - Objectives In older adults, both short and long sleep duration are associated with lower cognitive function, suggesting an inverted U-shaped association between sleep duration and cognitive outcomes. This study examined whether sleep duration is associated with (changes in) cognitive function in a middle-aged population. Methods In the Doetinchem Cohort Study, the cognitive function of 2970 men and women aged 41–75 years at baseline (1995–2007) was examined 2–3 times, with 5-year time intervals. Global cognitive function and the domains memory, information processing speed, and cognitive flexibility were assessed. In multivariable linear regression models, (change in) self-reported sleep duration was studied in association with the level and change in cognitive function. In a subsample of the population (n = 2587), the association of sleep duration and feeling rested with cognitive function was studied. Results Sleep duration of 9 h and more was statistically significantly associated with lower global cognitive function (p < 0.01), memory (p = 0.02), and flexibility (p = 0.03), compared to a sleep duration of 7 or 8 h. Among adults feeling frequently not well rested, both short and long sleep duration were associated with a lower speed of cognitive function. An inverted U-shaped association between sleep duration and cognitive function was observed for speed, flexibility, and global cognitive function. Sleep duration was not associated with change in cognitive function. Conclusions Middle-age adults with long sleep duration had a lower cognitive function.
AB - Objectives In older adults, both short and long sleep duration are associated with lower cognitive function, suggesting an inverted U-shaped association between sleep duration and cognitive outcomes. This study examined whether sleep duration is associated with (changes in) cognitive function in a middle-aged population. Methods In the Doetinchem Cohort Study, the cognitive function of 2970 men and women aged 41–75 years at baseline (1995–2007) was examined 2–3 times, with 5-year time intervals. Global cognitive function and the domains memory, information processing speed, and cognitive flexibility were assessed. In multivariable linear regression models, (change in) self-reported sleep duration was studied in association with the level and change in cognitive function. In a subsample of the population (n = 2587), the association of sleep duration and feeling rested with cognitive function was studied. Results Sleep duration of 9 h and more was statistically significantly associated with lower global cognitive function (p < 0.01), memory (p = 0.02), and flexibility (p = 0.03), compared to a sleep duration of 7 or 8 h. Among adults feeling frequently not well rested, both short and long sleep duration were associated with a lower speed of cognitive function. An inverted U-shaped association between sleep duration and cognitive function was observed for speed, flexibility, and global cognitive function. Sleep duration was not associated with change in cognitive function. Conclusions Middle-age adults with long sleep duration had a lower cognitive function.
KW - Cognitive function
KW - Cohort study
KW - Middle age
KW - Sleep duration
UR - http://www.scopus.com/inward/record.url?scp=85039866769&partnerID=8YFLogxK
U2 - 10.1016/j.sleep.2017.07.029
DO - 10.1016/j.sleep.2017.07.029
M3 - Article
AN - SCOPUS:85039866769
SN - 1389-9457
VL - 41
SP - 78
EP - 85
JO - Sleep Medicine
JF - Sleep Medicine
ER -