Lipoteichoic acid and peptidoglycan from Staphylococcus aureus synergistically induce neutrophil influx into the lungs of mice

Jaklien C. Leemans; Mirjam Heikens; Kok P.M. Van Kessel; Sandrine Florquin; Tom Van der Poll

doi:10.1128/CDLI.10.5.950-953.2003

Lipoteichoic acid and peptidoglycan from Staphylococcus aureus synergistically induce neutrophil influx into the lungs of mice

Jaklien C. Leemans^*, Mirjam Heikens, Kok P.M. Van Kessel, Sandrine Florquin, Tom Van der Poll

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

34 Citations (Scopus)

Abstract

Staphylococcus aureus is an important pathogen in nosocomial pneumonia. Lipoteichoic acid (LTA) and peptidoglycan (PepG) are part of the staphylococcal cell wall. Here we show that LTA and PepG act in synergy to cause polymorphonuclear cell recruitment in the pulmonary compartment during S. aureus pneumonia.

Original language	English
Pages (from-to)	950-953
Number of pages	4
Journal	Clinical and Diagnostic Laboratory Immunology
Volume	10
Issue number	5
DOIs	https://doi.org/10.1128/CDLI.10.5.950-953.2003
Publication status	Published - 1 Sept 2003
Externally published	Yes

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10.1128/CDLI.10.5.950-953.2003

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abstract = "Staphylococcus aureus is an important pathogen in nosocomial pneumonia. Lipoteichoic acid (LTA) and peptidoglycan (PepG) are part of the staphylococcal cell wall. Here we show that LTA and PepG act in synergy to cause polymorphonuclear cell recruitment in the pulmonary compartment during S. aureus pneumonia.",

author = "Leemans, {Jaklien C.} and Mirjam Heikens and {Van Kessel}, {Kok P.M.} and Sandrine Florquin and {Van der Poll}, Tom",

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T1 - Lipoteichoic acid and peptidoglycan from Staphylococcus aureus synergistically induce neutrophil influx into the lungs of mice

AU - Leemans, Jaklien C.

AU - Heikens, Mirjam

AU - Van Kessel, Kok P.M.

AU - Florquin, Sandrine

AU - Van der Poll, Tom

PY - 2003/9/1

Y1 - 2003/9/1

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AB - Staphylococcus aureus is an important pathogen in nosocomial pneumonia. Lipoteichoic acid (LTA) and peptidoglycan (PepG) are part of the staphylococcal cell wall. Here we show that LTA and PepG act in synergy to cause polymorphonuclear cell recruitment in the pulmonary compartment during S. aureus pneumonia.

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U2 - 10.1128/CDLI.10.5.950-953.2003

DO - 10.1128/CDLI.10.5.950-953.2003

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AN - SCOPUS:0141563808

SN - 1071-412X

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JO - Clinical and Diagnostic Laboratory Immunology

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ER -

Lipoteichoic acid and peptidoglycan from Staphylococcus aureus synergistically induce neutrophil influx into the lungs of mice

Abstract

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