TY - JOUR
T1 - Lipid Therapy for Intoxications
AU - Robben, Joris Henricus
AU - Dijkman, Marieke Annet
PY - 2017/3/1
Y1 - 2017/3/1
N2 - This review discusses the use of intravenous lipid emulsion (ILE) in the treatment of intoxications with lipophilic agents in veterinary medicine. Despite growing scientific evidence that ILE has merit in the treatment of certain poisonings, there is still uncertainty on the optimal composition of the lipid emulsion, the dosing, the mechanism of action, and the efficacy. Therefore, a critical view of the clinician on the applicability of this modality in intoxications is still warranted. The use of ILE therapy is advocated as an antidote in cases of intoxications with some lipophilic substances.
AB - This review discusses the use of intravenous lipid emulsion (ILE) in the treatment of intoxications with lipophilic agents in veterinary medicine. Despite growing scientific evidence that ILE has merit in the treatment of certain poisonings, there is still uncertainty on the optimal composition of the lipid emulsion, the dosing, the mechanism of action, and the efficacy. Therefore, a critical view of the clinician on the applicability of this modality in intoxications is still warranted. The use of ILE therapy is advocated as an antidote in cases of intoxications with some lipophilic substances.
KW - Emulsion
KW - Fat
KW - ILE
KW - Intralipid
KW - Lipid
KW - Lipid resuscitation therapy
KW - Poisoning
KW - Toxin
UR - http://www.scopus.com/inward/record.url?scp=85008172832&partnerID=8YFLogxK
U2 - 10.1016/j.cvsm.2016.10.018
DO - 10.1016/j.cvsm.2016.10.018
M3 - Review article
C2 - 28012788
AN - SCOPUS:85008172832
SN - 0195-5616
VL - 47
SP - 435
EP - 450
JO - Veterinary Clinics of North America - Small Animal Practice
JF - Veterinary Clinics of North America - Small Animal Practice
IS - 2
ER -