Life and death as a T lymphocyte: from immune protection to HIV pathogenesis

Nienke Vrisekoop; Judith N Mandl; Ronald N Germain

doi:10.1186/jbiol198

Life and death as a T lymphocyte: from immune protection to HIV pathogenesis

Nienke Vrisekoop
, Judith N Mandl
, Ronald N Germain

Research output: Contribution to journal › Review article › peer-review

Abstract

Detailed analysis of T cell dynamics in humans is challenging and mouse models can be important tools for characterizing T cell dynamic processes. In a paper just published in Journal of Biology, Marques et al. suggest that a mouse model with its activated CD4(+) T cells are deleted has relevance for HIV infection.

Original language	English
Pages (from-to)	91
Journal	Journal of biology
Volume	8
Issue number	10
DOIs	https://doi.org/10.1186/jbiol198
Publication status	Published - 2009
Externally published	Yes

Keywords

Animals
CD4-Positive T-Lymphocytes/immunology
CD8-Positive T-Lymphocytes/immunology
Disease Models, Animal
HIV/pathogenicity
HIV Infections/immunology
Lymphocyte Activation
Mice
Mice, Transgenic

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10.1186/jbiol198

Cite this

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title = "Life and death as a T lymphocyte: from immune protection to HIV pathogenesis",

abstract = "Detailed analysis of T cell dynamics in humans is challenging and mouse models can be important tools for characterizing T cell dynamic processes. In a paper just published in Journal of Biology, Marques et al. suggest that a mouse model with its activated CD4(+) T cells are deleted has relevance for HIV infection.",

keywords = "Animals, CD4-Positive T-Lymphocytes/immunology, CD8-Positive T-Lymphocytes/immunology, Disease Models, Animal, HIV/pathogenicity, HIV Infections/immunology, Lymphocyte Activation, Mice, Mice, Transgenic",

author = "Nienke Vrisekoop and Mandl, \{Judith N\} and Germain, \{Ronald N\}",

year = "2009",

doi = "10.1186/jbiol198",

language = "English",

volume = "8",

pages = "91",

journal = "Journal of biology",

issn = "1478-5854",

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T2 - from immune protection to HIV pathogenesis

AU - Vrisekoop, Nienke

AU - Mandl, Judith N

AU - Germain, Ronald N

PY - 2009

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N2 - Detailed analysis of T cell dynamics in humans is challenging and mouse models can be important tools for characterizing T cell dynamic processes. In a paper just published in Journal of Biology, Marques et al. suggest that a mouse model with its activated CD4(+) T cells are deleted has relevance for HIV infection.

AB - Detailed analysis of T cell dynamics in humans is challenging and mouse models can be important tools for characterizing T cell dynamic processes. In a paper just published in Journal of Biology, Marques et al. suggest that a mouse model with its activated CD4(+) T cells are deleted has relevance for HIV infection.

KW - Animals

KW - CD4-Positive T-Lymphocytes/immunology

KW - CD8-Positive T-Lymphocytes/immunology

KW - Disease Models, Animal

KW - HIV/pathogenicity

KW - HIV Infections/immunology

KW - Lymphocyte Activation

KW - Mice

KW - Mice, Transgenic

U2 - 10.1186/jbiol198

DO - 10.1186/jbiol198

M3 - Review article

C2 - 19951397

SN - 1478-5854

VL - 8

SP - 91

JO - Journal of biology

JF - Journal of biology

IS - 10

ER -

Life and death as a T lymphocyte: from immune protection to HIV pathogenesis

Abstract

Keywords

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