Levels of soluble receptors for tumor necrosis factor type I and type II in paired synovial fluids of arthritis patients

A M Miltenburg; D Aderka; J M van Laar; D Wallach; F C Breedveld

Levels of soluble receptors for tumor necrosis factor type I and type II in paired synovial fluids of arthritis patients

A M Miltenburg
, D Aderka
, J M van Laar
, D Wallach
, F C Breedveld

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

The objective of this study was to determine whether levels of soluble receptors for tumor necrosis factor type I and type II (sTNF-RI and sTNF-RII) as measured in paired synovial fluids (SF) of arthritis patients are associated with clinical or laboratory parameters of local inflammation. sTNF-RI and -RII were measured by ELISA. We found that sTNF-RI and -RII did not correlate with activity of local inflammation. sTNF-RI levels correlated with sTNF-RII concentrations. We concluded that sTNF-RI and -II did not represent markers for local disease activity in arthritis patients.

Original language	English
Pages (from-to)	117-9
Number of pages	3
Journal	Rheumatology International
Volume	13
Issue number	3
Publication status	Published - 1993
Externally published	Yes

Keywords

Adult
Aged
Arthritis
Arthritis, Rheumatoid
Humans
Middle Aged
Receptors, Tumor Necrosis Factor
Severity of Illness Index
Synovial Fluid
Journal Article
Research Support, Non-U.S. Gov't

Cite this

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title = "Levels of soluble receptors for tumor necrosis factor type I and type II in paired synovial fluids of arthritis patients",

abstract = "The objective of this study was to determine whether levels of soluble receptors for tumor necrosis factor type I and type II (sTNF-RI and sTNF-RII) as measured in paired synovial fluids (SF) of arthritis patients are associated with clinical or laboratory parameters of local inflammation. sTNF-RI and -RII were measured by ELISA. We found that sTNF-RI and -RII did not correlate with activity of local inflammation. sTNF-RI levels correlated with sTNF-RII concentrations. We concluded that sTNF-RI and -II did not represent markers for local disease activity in arthritis patients.",

keywords = "Adult, Aged, Arthritis, Arthritis, Rheumatoid, Humans, Middle Aged, Receptors, Tumor Necrosis Factor, Severity of Illness Index, Synovial Fluid, Journal Article, Research Support, Non-U.S. Gov't",

author = "Miltenburg, \{A M\} and D Aderka and \{van Laar\}, \{J M\} and D Wallach and Breedveld, \{F C\}",

year = "1993",

language = "English",

volume = "13",

pages = "117--9",

journal = "Rheumatology International",

issn = "0172-8172",

publisher = "Springer Science and Business Media Deutschland GmbH",

number = "3",

}

TY - JOUR

T1 - Levels of soluble receptors for tumor necrosis factor type I and type II in paired synovial fluids of arthritis patients

AU - Miltenburg, A M

AU - Aderka, D

AU - van Laar, J M

AU - Wallach, D

AU - Breedveld, F C

PY - 1993

Y1 - 1993

N2 - The objective of this study was to determine whether levels of soluble receptors for tumor necrosis factor type I and type II (sTNF-RI and sTNF-RII) as measured in paired synovial fluids (SF) of arthritis patients are associated with clinical or laboratory parameters of local inflammation. sTNF-RI and -RII were measured by ELISA. We found that sTNF-RI and -RII did not correlate with activity of local inflammation. sTNF-RI levels correlated with sTNF-RII concentrations. We concluded that sTNF-RI and -II did not represent markers for local disease activity in arthritis patients.

AB - The objective of this study was to determine whether levels of soluble receptors for tumor necrosis factor type I and type II (sTNF-RI and sTNF-RII) as measured in paired synovial fluids (SF) of arthritis patients are associated with clinical or laboratory parameters of local inflammation. sTNF-RI and -RII were measured by ELISA. We found that sTNF-RI and -RII did not correlate with activity of local inflammation. sTNF-RI levels correlated with sTNF-RII concentrations. We concluded that sTNF-RI and -II did not represent markers for local disease activity in arthritis patients.

KW - Adult

KW - Aged

KW - Arthritis

KW - Arthritis, Rheumatoid

KW - Humans

KW - Middle Aged

KW - Receptors, Tumor Necrosis Factor

KW - Severity of Illness Index

KW - Synovial Fluid

KW - Journal Article

KW - Research Support, Non-U.S. Gov't

M3 - Article

C2 - 8235290

SN - 0172-8172

VL - 13

SP - 117

EP - 119

JO - Rheumatology International

JF - Rheumatology International

IS - 3

ER -

Levels of soluble receptors for tumor necrosis factor type I and type II in paired synovial fluids of arthritis patients

Abstract

Keywords

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