TY - JOUR
T1 - Left ventricular unloading during veno-arterial ECMO
T2 - a review of percutaneous and surgical unloading interventions
AU - Donker, Dirk W.
AU - Brodie, Daniel
AU - Henriques, José P.S.
AU - Broomé, Michael
N1 - Funding Information:
The authors disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: Michael Broomé’s (MB) research during the years 2013-2015 was funded by The Swedish Research Council Grant 2012-2800 and, in 2017, supported by the Stockholm County Council (ALF project).
Publisher Copyright:
© The Author(s) 2018.
PY - 2019/3
Y1 - 2019/3
N2 - Short-term mechanical support by veno-arterial extracorporeal membrane oxygenation (VA ECMO) is more and more applied in patients with severe cardiogenic shock. A major shortcoming of VA ECMO is its variable, but inherent increase of left ventricular (LV) mechanical load, which may aggravate pulmonary edema and hamper cardiac recovery. In order to mitigate these negative sequelae of VA ECMO, different adjunct LV unloading interventions have gained a broad interest in recent years. Here, we review the whole spectrum of percutaneous and surgical techniques combined with VA ECMO reported to date.
AB - Short-term mechanical support by veno-arterial extracorporeal membrane oxygenation (VA ECMO) is more and more applied in patients with severe cardiogenic shock. A major shortcoming of VA ECMO is its variable, but inherent increase of left ventricular (LV) mechanical load, which may aggravate pulmonary edema and hamper cardiac recovery. In order to mitigate these negative sequelae of VA ECMO, different adjunct LV unloading interventions have gained a broad interest in recent years. Here, we review the whole spectrum of percutaneous and surgical techniques combined with VA ECMO reported to date.
KW - cardiogenic shock
KW - cardiovascular modeling
KW - computer simulation
KW - left ventricular unloading
KW - veno-arterial extracorporeal membrane oxygenation (VA ECMO)
KW - Extracorporeal Membrane Oxygenation/methods
KW - Heart Ventricles/metabolism
KW - Humans
KW - Shock, Cardiogenic/therapy
UR - http://www.scopus.com/inward/record.url?scp=85052579505&partnerID=8YFLogxK
U2 - 10.1177/0267659118794112
DO - 10.1177/0267659118794112
M3 - Review article
C2 - 30112975
SN - 0267-6591
VL - 34
SP - 98
EP - 105
JO - Perfusion
JF - Perfusion
IS - 2
ER -