TY - JOUR
T1 - Left atrial appendage closure guided by 3D computed tomography printing technology
T2 - A case control study
AU - Conti, Michele
AU - Marconi, Stefania
AU - Muscogiuri, Giuseppe
AU - Guglielmo, Marco
AU - Baggiano, Andrea
AU - Italiano, Gianpiero
AU - Mancini, Maria Elisabetta
AU - Auricchio, Ferdinando
AU - Andreini, Daniele
AU - Rabbat, Mark G.
AU - Guaricci, Andrea Igoren
AU - Fassini, Gaetano
AU - Gasperetti, Alessio
AU - Costa, Fabrizio
AU - Tondo, Claudio
AU - Maltagliati, Anna
AU - Pepi, Mauro
AU - Pontone, Gianluca
N1 - Publisher Copyright:
© 2019 Society of Cardiovascular Computed Tomography
PY - 2019/11/1
Y1 - 2019/11/1
N2 - Background: We sought to evaluate the additional value of left atrial appendage (LAA) 3D printing derived from computed tomography (CCT) in determining the size for LAA occlusion (LAAO) devices as compared to standard measurement by using occurrence of LAA leak as endpoint. Methods: We evaluated 6 patients with LAA leak (cases) and 14 matched patients without LAA leak (controls) after LAAO. For each group, a patient-specific 3D printed model of LAA was manufactured using CT pre-operative images. The size recommended by the 3D printed model was compared with the size of the implanted device. Results: Compared to the 3D printed model, 55% of the devices were underestimated, the two sizing approaches agreed in 35% of the patients, while the 3D printed model overestimated the size in 10% of patients. The prevalence of LAA leak was significantly higher in the subset of patients with underestimation of prosthesis implanted with the standard approach as compared to the other patients (p = 0.019). Conclusion: 3D printing of the LAA may provide additional value to standard practice for LAAO device prosthesis sizing with the potential impact to reduce LAA leak.
AB - Background: We sought to evaluate the additional value of left atrial appendage (LAA) 3D printing derived from computed tomography (CCT) in determining the size for LAA occlusion (LAAO) devices as compared to standard measurement by using occurrence of LAA leak as endpoint. Methods: We evaluated 6 patients with LAA leak (cases) and 14 matched patients without LAA leak (controls) after LAAO. For each group, a patient-specific 3D printed model of LAA was manufactured using CT pre-operative images. The size recommended by the 3D printed model was compared with the size of the implanted device. Results: Compared to the 3D printed model, 55% of the devices were underestimated, the two sizing approaches agreed in 35% of the patients, while the 3D printed model overestimated the size in 10% of patients. The prevalence of LAA leak was significantly higher in the subset of patients with underestimation of prosthesis implanted with the standard approach as compared to the other patients (p = 0.019). Conclusion: 3D printing of the LAA may provide additional value to standard practice for LAAO device prosthesis sizing with the potential impact to reduce LAA leak.
KW - 3D printing technology
KW - Atrial fibrillation
KW - Percutaneous left atrial appendage closure
UR - http://www.scopus.com/inward/record.url?scp=85055691964&partnerID=8YFLogxK
U2 - 10.1016/j.jcct.2018.10.024
DO - 10.1016/j.jcct.2018.10.024
M3 - Article
C2 - 30389341
AN - SCOPUS:85055691964
SN - 1934-5925
VL - 13
SP - 336
EP - 339
JO - Journal of cardiovascular computed tomography
JF - Journal of cardiovascular computed tomography
IS - 6
ER -