Latent class analysis-based subgroups and response to corticosteroids in hospitalised community-acquired pneumonia patients: a validation study

Esther Wittermans; Philip A van der Zee; Hongchao Qi; Jan C Grutters; G Paul Voorn; Willem Jan W Bos; Ewoudt M W van de Garde; Henrik Endeman

doi:10.1183/23120541.00577-2022

Latent class analysis-based subgroups and response to corticosteroids in hospitalised community-acquired pneumonia patients: a validation study

Esther Wittermans, Philip A van der Zee, Hongchao Qi, Jan C Grutters, G Paul Voorn, Willem Jan W Bos, Ewoudt M W van de Garde, Henrik Endeman

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Abstract

In patients with community-acquired pneumonia, LCA can identify robust prognostic subgroups based on clinical and inflammatory parameters. Yet, these subgroups have not proven robust in predicting response to adjunctive dexamethasone treatment. https://bit.ly/3O5eaxz.

Original language	English
Article number	00577-2022
Journal	ERJ Open Research
Volume	9
Issue number	2
DOIs	https://doi.org/10.1183/23120541.00577-2022
Publication status	Published - Mar 2023

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00577-2022.fullFinal published version, 374 KBLicence: CC BY-NC

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@article{a04aaeaebfce4de5bf30008929b31df9,

title = "Latent class analysis-based subgroups and response to corticosteroids in hospitalised community-acquired pneumonia patients: a validation study",

abstract = " In patients with community-acquired pneumonia, LCA can identify robust prognostic subgroups based on clinical and inflammatory parameters. Yet, these subgroups have not proven robust in predicting response to adjunctive dexamethasone treatment. https://bit.ly/3O5eaxz. ",

author = "Esther Wittermans and \{van der Zee\}, \{Philip A\} and Hongchao Qi and Grutters, \{Jan C\} and Voorn, \{G Paul\} and Bos, \{Willem Jan W\} and \{van de Garde\}, \{Ewoudt M W\} and Henrik Endeman",

note = "Funding Information: Conflict of interest: E. Wittermans has nothing to disclose. P.A. van der Zee has nothing to disclose. H. Qi has nothing to disclose. J.C. Grutters has nothing to disclose. G.P. Voorn has nothing to disclose. W.J.W. Bos reports grants from Zilveren Kruis Insurance outside the submitted work. E.M.W. van de Garde has nothing to disclose. H. Endeman has nothing to disclose.",

year = "2023",

month = mar,

doi = "10.1183/23120541.00577-2022",

language = "English",

volume = "9",

journal = "ERJ Open Research",

issn = "2312-0541",

publisher = "European Respiratory Society",

number = "2",

}

TY - JOUR

T1 - Latent class analysis-based subgroups and response to corticosteroids in hospitalised community-acquired pneumonia patients

T2 - a validation study

AU - Wittermans, Esther

AU - van der Zee, Philip A

AU - Qi, Hongchao

AU - Grutters, Jan C

AU - Voorn, G Paul

AU - Bos, Willem Jan W

AU - van de Garde, Ewoudt M W

AU - Endeman, Henrik

N1 - Funding Information: Conflict of interest: E. Wittermans has nothing to disclose. P.A. van der Zee has nothing to disclose. H. Qi has nothing to disclose. J.C. Grutters has nothing to disclose. G.P. Voorn has nothing to disclose. W.J.W. Bos reports grants from Zilveren Kruis Insurance outside the submitted work. E.M.W. van de Garde has nothing to disclose. H. Endeman has nothing to disclose.

PY - 2023/3

Y1 - 2023/3

N2 - In patients with community-acquired pneumonia, LCA can identify robust prognostic subgroups based on clinical and inflammatory parameters. Yet, these subgroups have not proven robust in predicting response to adjunctive dexamethasone treatment. https://bit.ly/3O5eaxz.

AB - In patients with community-acquired pneumonia, LCA can identify robust prognostic subgroups based on clinical and inflammatory parameters. Yet, these subgroups have not proven robust in predicting response to adjunctive dexamethasone treatment. https://bit.ly/3O5eaxz.

UR - https://www.scopus.com/pages/publications/85150170781

U2 - 10.1183/23120541.00577-2022

DO - 10.1183/23120541.00577-2022

M3 - Letter

C2 - 36891066

SN - 2312-0541

VL - 9

JO - ERJ Open Research

JF - ERJ Open Research

IS - 2

M1 - 00577-2022

ER -

Latent class analysis-based subgroups and response to corticosteroids in hospitalised community-acquired pneumonia patients: a validation study

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