TY - JOUR
T1 - KRS
T2 - A cut away from release in exosomes
AU - Rabouille, Catherine
PY - 2017/7/1
Y1 - 2017/7/1
N2 - Cancer cells often trigger an inflammatory process, which in some cases may be driven by the presence of lysyltRNA synthetase (KRS) in the medium. Kim et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201605118) now demonstrate that cleavage of the KRS by caspase-8 inside cells triggers its interaction with syntenin and its release in inflammatory exosomes.
AB - Cancer cells often trigger an inflammatory process, which in some cases may be driven by the presence of lysyltRNA synthetase (KRS) in the medium. Kim et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201605118) now demonstrate that cleavage of the KRS by caspase-8 inside cells triggers its interaction with syntenin and its release in inflammatory exosomes.
UR - http://www.scopus.com/inward/record.url?scp=85021854087&partnerID=8YFLogxK
U2 - 10.1083/jcb.201706039
DO - 10.1083/jcb.201706039
M3 - Comment/Letter to the editor
AN - SCOPUS:85021854087
SN - 0021-9525
VL - 216
SP - 1891
EP - 1893
JO - Journal of Cell Biology
JF - Journal of Cell Biology
IS - 7
ER -