KPC-like carbapenemase-producing enterobacteriaceae colonizing patients in Europe and Israel

A. Baraniak, R. Izdebski, J. Fiett, M. Herda, L. P G Derde, M. J M Bonten, A. Adler, Y. Carmeli, H. Goossens, W. Hryniewicz, C. Brun-Buisson, M. Gniadkowski*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)
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Abstract

In a 2008-2011 survey, 17,945 patients in 18 hospital units in Europe and Israel were screened for carriage of Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae, resulting in identification of 124 positive patients. The isolates were dominated by Klebsiella pneumoniae sequence type 258 (ST258) KPC-2 and ST512 KPC-3, mainly from Greece and Italy, respectively, whereas Israeli isolates were of diverse species, clones, and KPC variants. Various blaKPC platforms were observed, among which IncFIIK-FIBK plasmids with blaKPC-2/-3 genes in the Tn4401a transposon prevailed.

Original languageEnglish
Pages (from-to)1912-1917
Number of pages6
JournalAntimicrobial Agents and Chemotherapy
Volume60
Issue number3
DOIs
Publication statusPublished - 1 Mar 2016

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